View source for Vein

{{otheruses}}
{{Nofootnotes|date=June 2008}}
{{Infobox Anatomy |
Name         = {{PAGENAME}} |
Latin        = vena  |
GraySubject  = |
GrayPage     = |
Image        = Venous system en.svg |
Caption      = The main veins in the human body |
Image2       = |guts
Caption2     = |
Precursor    = |
System       = |nuts
Artery       = |
Vein         = |
Nerve        = |
Lymph        = |
MeshName     = |
MeshNumber   = |
}}
In the [[circulatory system]], '''veins''' (from the [[Latin language|Latin]] ''vena'') are [[blood vessels]] that carry [[blood]] '''towards the [[heart]]'''. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are the [[pulmonary vein|pulmonary]] and [[umbilical vein]]s, both of which carry oxygenated blood to the heart. Veins differ from [[artery|arteries]] in structure and function; for example, arteries are more muscular than veins and they carry blood away from the heart.

== Anatomy ==
[[File:Veincrosssection.png|thumb|right|200px|Cross section of a vein showing a valve that prevents backflow]]
In general, veins function to return deoxygenated blood to the [[heart]], and are essentially tubes that collapse when their [[Lumen (anatomy)|lumens]] are not filled with blood. The thick outermost layer of a vein is made of [[connective tissue]], called tunica adventitia or tunica externa.  Deeper are bands of [[smooth muscle]] called tunica media, which are, in general, thin, as veins do not function primarily in a contractile manner. The interior is lined with [[Endothelium|endothelial cells]] called tunica intima.  Most veins have one-way flaps called venous valves that prevent blood from flowing back and pooling in the lower extremities due to the effects of [[gravity]]. These are infoldings of the tunica intima. The precise location of veins is much more variable from person to person than that of [[Artery|arteries]].<ref>{{cite book | last = Maton | first = Anthea | authorlink = | coauthors = Jean Hopkins, Charles William McLaughlin, Alexandra Senckowski, Susan Johnson, Maryanna Quon Warner, David LaHart, Jill D. Wright | title = Human Biology and Health | publisher = Prentice Hall | date = 1993 | location = Englewood Cliffs, New Jersey | pages = | url = | doi = | id = | isbn = 0-13-981176-1}}</ref>

=== Notable veins and vein systems ===
The greater saphenous vein is the most important superficial vein of the lower limb. First described by the [[Persia|Persian]] physician [[Avicenna]], this vein derives its name from the word ''safina'', meaning "hidden". This vein is "hidden" in its own [[fascial compartment]] in the thigh and exits the fascia only near the knee. Incompetence of this vein is an important cause of [[varicose vein]]s of lower limbs.

The [[pulmonary vein]]s carry relatively oxygenated blood from the lungs to the heart. The [[superior vena cava|superior]] and [[inferior vena cava|inferior venae cavae]] carry relatively deoxygenated blood from the upper and lower systemic circulations, respectively.

A [[portal venous system]] is a series of veins or venules that directly connect two [[capillary bed]]s. Examples of such systems include the [[hepatic portal vein]] and [[hypophyseal portal system]]

=== Color ===
Vein color is determined in large part by the color of [[venous blood]], which is usually dark red as a result of its low oxygen content. Veins appear blue because the [[subcutis|subcutaneous fat]] absorbs low-frequency light, permitting only the highly energetic blue wavelengths to penetrate through to the dark vein and reflect off.

== Function ==
Veins serve to return blood from organs to the heart.  In [[systemic circulation]] oxygenated blood is pumped by the [[left ventricle]] through the [[artery|arteries]] to the muscles and organs of the body, where its nutrients and gases are exchanged at [[capillary|capillaries]], entering the veins filled with cellular waste and [[carbon dioxide]].  The de-[[oxygen]]ated blood is taken by veins to the [[right atrium]] of the heart, which transfers the blood to the [[right ventricle]], where it is then pumped through the pulmonary arteries to the [[lung]]s.  In [[pulmonary circulation]] the [[pulmonary vein]]s return oxygenated blood from the lungs to the [[left atrium]], which empties into the left ventricle, completing the cycle of blood circulation.

The return of blood to the heart is assisted by the action of the [[skeletal-muscle pump]], which helps maintain the extremely low [[blood pressure]] of the venous system.  [[Fainting]] can be caused by failure of the skeletal-muscular pump.  Long periods standing can result in blood pooling in the legs, with blood pressure too high to return blood to the heart.  [[Neurogenic shock|Neurogenic]] and [[shock (circulatory)#Hypovolaemic shock|hypovolaemic shock]] can also cause fainting.  In these cases, the smooth muscles surrounding the veins become slack and the veins fill with the majority of the blood in the body, keeping blood away from the brain and causing unconsciousness.

The arteries are perceived as carrying oxygenated blood to the tissues, while veins carry deoxygenated blood back to the heart. This is true of the systemic circulation, by far the larger of the two circuits of blood in the body, which transports oxygen from the heart to the tissues of the body.  However, in pulmonary circulation, the arteries carry deoxygenated blood from the heart to the lungs, and veins return blood from the lungs to the heart.  The difference between veins and arteries is their direction of flow (out of the heart by arteries, returning to the heart for veins), not their oxygen content.  In addition, deoxygenated blood that is carried from the tissues back to the heart for reoxygenation in systemic circulation still carries some oxygen, though it is considerably less than that carried by the systemic arteries or pulmonary veins.

Although most veins take blood back to the heart, there is an exception. Portal veins carry blood between capillary beds. For example, the hepatic portal vein takes blood from the capillary beds in the digestive tract and transports it to the capillary beds in the liver. The blood is then drained in the gastrointestinal tract and spleen, where it is taken up by the hepatic veins, and blood is taken back into the heart. Since this is an important function in mammals, damage to the hepatic portal vein can be dangerous. Blood clotting in the hepatic portal vein can cause portal hypertension, which results in a decrease of blood fluid to the liver.

== Classification ==
Veins are classified in a number of ways, including superficial vs. deep, pulmonary vs. systemic, and large vs. small.

;Superficial veins
:[[Superficial vein]]s are those whose course is close to the surface of the body, and have no corresponding arteries.

;Deep veins
:[[Deep vein]]s are deeper in the body and have corresponding arteries.

;Pulmonary veins
:The [[pulmonary vein]]s are a set of veins that deliver oxygenated blood from the [[lung]]s to the heart.

;Systemic veins
:[[Systemic vein]]s drain the tissues of the body and deliver deoxygenated blood to the heart.

== Clinical significance ==
[[File:Venous valve.svg|right|thumb|210px|Venous valves prevent reverse blood flow.]]

=== Phlebology ===
Phlebology is the medical discipline that involves the diagnosis and treatment of disorders of venous origin. Diagnostic techniques used include the history and physical examination, venous imaging techniques and laboratory evaluation related to venous [[Thrombosis|thromboembolism]]. The American Medical Association has added phlebology to their list of self-designated practice specialties. A medical specialist in Phlebology is termed a [[Phlebologist]]. A related image is called a [[Impedance phlebography|phlebography]]

The [[American College of Phlebology]] (ACP) is a professional organization of physicians and healthcare professionals from a variety of backgrounds. ACP meetings are conducted to facilitate learning and sharing of knowledge regarding venous disease.  The equivalent body for countries in the Pacific is the [[Australasian College of Phlebology]], active in Australia and New Zealand.

The [[American Venous Forum]] (AVF) is the leading academic international consortium of venous and lymphatic specialists dedicated to improving patient care. The highest-quality research in clinical and basic sciences is reported at the AVF annual meetings, along with the reports on new developments in diagnosis and treatment of venous diseases. The main body of the AVF consists of vascular surgeons and other physicians who specialized in management of not only simple varicose veins but the whole spectrum of venous and lymphatic diseases from congenital abnormalities to deep vein thrombosis to chronic venous diseases.


=== Venous diseases ===
==== Venous insufficiency ====
{{main|Chronic venous insufficiency}}

Venous insufficiency is the most common disorder of the venous system, and is usually manifested as [[Telangiectasia|spider veins]] or [[varicose veins]]. Several varieties of treatments are used, depending on the patient's particular type and pattern of veins and on the physician's preferences.  Treatment can include [[Somnoplasty|radiofrequency ablation]], [[vein stripping]], [[ambulatory phlebectomy]], foam [[sclerotherapy]], [[laser]]s, or compression.

[[Postphlebitic syndrome]] is venous insufficiency that develops following [[deep vein thrombosis]].<ref name="pmid16822286">{{cite journal |author=Kahn SR |title=The post-thrombotic syndrome: progress and pitfalls |journal=Br. J. Haematol. |volume=134 |issue=4 |pages=357–65 |year=2006 |month=August |pmid=16822286 |doi=10.1111/j.1365-2141.2006.06200.x |url=}}</ref>

==== Deep vein thrombosis ====
{{main|Deep vein thrombosis}}

Deep-vein thrombosis is a condition in which a [[Thrombus|blood clot]] forms in a deep vein, which can lead to [[pulmonary embolism]] and chronic venous insufficiency.

==== Thrombophlebitis ====
{{main|Thrombophlebitis}}

Thrombophlebitis is an inflammatory condition of the veins related to [[thrombus|blood clots]].

== See also ==
* [[Artery]]
* [[Deep vein]]
* [[Deep vein thrombosis]]
* [[Peripheral vein]]
* [[Phlebologist]]
* [[Pulmonary circulation]]
* [[Superficial vein]]
* [[Varicose veins]]

== References ==
{{Refimprove|date=January 2008}}
{{reflist}}

== External links ==
{{wiktionary}}
* [http://www.merck.com/mmhe/sec03/ch036/ch036a.html Merck Manual article on veins.]
* [http://www.veinforum.org]
* [http://www.phlebology.org/ American College of Phlebology]
* [http://www.americanboardofphlebology.org/ American Board of Phlebology]
* [http://www.phlebologyfoundation.org/ American College of Phlebology Foundation]
* [http://www.phlebology.com.au/forms/selmenu.aspx?selmenu=5 Australasian College of Phlebology] Information from the Australasian College of Phlebology Website
* [http://ocw.dmc.keio.ac.jp/economics/02A-003_e/lecture_contents/ln03e.pdf In economics: Arterial and venous industries]
* [http://www.simmed.com/Demo/Default.aspx Animated Venous Access tutorials]

=== Scientific publications ===
* [http://phleb.rsmjournals.com/ Phlebology: The Journal of Venous Disease]
* [http://www.medi-data.co.uk/phlebology/index.htm Phlebology: 1986-1999]

{{System and organs}}
{{cardiovascular_system}}
{{Veins of the head and neck}}
{{Veins of the upper extremity}}
{{Veins of the thorax and vertebral column}}
{{Veins of the abdomen and pelvis}}
{{Veins of the lower extremity}}

[[Category:Cardiovascular system]]
[[Category:Veins]]

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[[ar:وريد]]
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