View source for Aceclofenac

{{Drugbox
| IUPAC_name        = 2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid
| image             = Aceclofenac.png
| CAS_number        = 89796-99-6
| ATC_prefix        = M01
| ATC_suffix        = AB16
| ATC_supplemental  = {{ATC|M02|AA25}}
| PubChem           = 71771
| DrugBank          = 
| C=16|H=13|Cl=2|N=1|O=4
| molecular_weight  = 354.18472 g/mol
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category=  
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  POM
| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = oral, topical
}}

'''Aceclofenac''' is a [[non-steroidal anti-inflammatory drug]].  It is manufactured by [[Intas Biopharmaceuticals]], under the tradename '''Hifenac''' in various forms (tablets, gel, injection etc.). '''Kaptab Pharmaceuticals''' manufactures Aceclofenac in combination with Paracetamol under the trade name '''"Cincofen"''' (Aceclofenac 100&nbsp;mg + Paracetamol 500&nbsp;mg)

It is used for the relief of pain and inflammation in [[rheumatoid arthritis]], [[osteoarthritis]] and [[ankylosing spondylitis]].  The dose is 100&nbsp;mg twice daily.
It should not be given to people with [[porphyria]] or breast-feeding mothers, and is not recommended for children.

Aceclofenac has higher anti-inflammatory action than conventional NSAIDS. It is a [[cytokine]] inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of [[prostaglandin]]s (chemicals in the body) which cause pain, swelling and inflammation.

== References ==
* British National Formulary 55, March 2008; ISBN 978 085369 776 3 p.&nbsp;537

{{Anti-inflammatory and antirheumatic products}}
{{NSAIDs}}
{{Analgesics}}

*BRAND NAME:

AS RANGE AVAILABLE IN VARIOUS FORMS:
*PAINO (ACECLOFENAC 100&nbsp;mg tablet, ESKAYEF BANGLADESH LIMITED)
*AS-100  (ACECLOFENAC 100&nbsp;mg)
*AS PLUS (with PARACETAMOL 500&nbsp;mg)
*AS SR   (SUSTAINED RELEASED 200&nbsp;mg)
*AS MR   (with TIZANIDINE 2&nbsp;mg)
*AS GEL  (with OLIUM LINE,METHYL SALICATE, CAPSISUM)
*AS MYO  (with THIOCOLCHICOSIDE 4&nbsp;mg)
*AS 15   (with SERRATIOPEPTIDASE 15&nbsp;mg)

[[Category:Aromatic amines]]
[[Category:Carboxylic acids]]
[[Category:Organochlorides]]
[[Category:Acetate esters]]


{{musculoskeletal-drug-stub}}
{{analgesic-stub}}

[[es:Aceclofenaco]]
[[fr:Acéclofénac]]
[[it:Aceclofenac]]
[[pt:Aceclofenaco]]
[[ru:Ацеклофенак]]
[[vi:Aceclofenac]]
[[Category:2Fix]]