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'''Cold Capsule IV''' and '''Cold Capsule V''' were [[extended release]] [[mouth|oral]] [[Capsule (pharmacy)|capsules]] ([[pill]]) used to control cold symptoms.

==Composition==
Both products contained [[chlorpheniramine maleate]] (an [[antihistamine]]) and [[phenylpropanolamine hydrochloride]] (a [[decongestant]]) but differed in their doses.  Both products contained 75 [[Milligram|mg]] of phenylpropanolamine hydrochloride, but Cold Capsule IV contained 12 [[Milligram|mg]] chlorpheniramine maleate while Cold Capsule V had 8 mg<ref>[http://www.drugpatentwatch.com/basic/preview/detail/index.php?searchtype=alpha&category=Tradename&searchstring=COLD%20CAPSULE%20IV DrugPatentWatch.com Basic Plan - Drug patent expirations dates, exclusivity, sales, patent details, case histories, and more<!-- Bot generated title -->]</ref>
.  

==History==
They was manufactured by Graham DM and both approved for use by the [[U.S. Food and Drug Administration]] in 1985.

In 2000 the FDA issued an advisory for all products containing phenylpropanolamine due to the risk of [[stroke]]<ref>http://www.fda.gov/cder/drug/infopage/ppa/advisory.htm Food and Drug Administration Public Health Advisory, "Safety of Phenylpropanolamine", ''www.FDA.gov</ref> and recommended their recall.  Both Cold Capsule products are now [[Discontinuation|Discontinued]].

==References==
<references/>


{{Pharma-stub}}

[[Category:Decongestants]]
[[Category:H1 receptor antagonists]]
[[Category:2Fix]]