View source for Lymphocytic colitis

{{Infobox_Disease |
  Name           = {{PAGENAME}} |
  Image          = |
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  DiseasesDB     = 30087 |
  ICD10          = |
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  MedlinePlus    = |
  eMedicineSubj  = med |
  eMedicineTopic = 1351 |
  MeshID         = D046730 |
}}
'''Lymphocytic colitis''', a subtype of [[microscopic colitis]], is a rare condition characterized by chronic non-bloody watery [[diarrhea]]. The [[colonoscopy]] is normal but the mucosal biopsy reveals an accumulation of [[lymphocytes]] in the colonic epithelium and connective tissue (lamina propria). [[Collagenous colitis]] shares this feature but additionally shows a distinctive thickening of the subepithelial collagen table. The peak incidence of lymphocytic colitis is in persons over age 50; the disease affects women more than men.

==Causes==
No definite etiology has been determined. Some reports have implicated long-term usage of [[Non-steroidal anti-inflammatory drugs|NSAIDs]], [[antidepressants]] specifically Sertraline (Zoloft), and other drugs; and overactive immune responses are also suspected.

==Treatment==
Over-the-counter antidiarrheal drugs are effective for many people with lymphocytic colitis. Anti-inflammatory drugs, such as [[Salicylic acid| salicylates]] may also help. [[Corticosteroids]] or [[Mesalazine]]s may be prescribed for people who do not respond to other drug treatment. The long-term prognosis for this disease is not clear.

==See also==
*[[Colitis]]
*[[Collagenous colitis]]

==External links==
*[http://digestive.niddk.nih.gov/ddiseases/pubs/collagenouscolitis/index.htm Collagenous Colitis and Lymphocytic Colitis]
*[http://www.diseasesdatabase.com/umlsdef.asp?glngUserChoice=30087 Diseases Database]
*[http://www.gpnotebook.co.uk/simplepage.cfm?ID=1697972300 GPNotebook]
*[http://www.emedicine.com/med/topic1351.htm eMedicine.com]
*[http://www.merck.com/mmhe/print/sec09/ch126/ch126d.html Merck Manual]

==References==
*[http://hopkins-gi.nts.jhu.edu/pages/latin/templates/index.cfm?pg=disease1&disease=29&organ=6&lang_id=1 Gasteroenterology and Hepatology Resource Center, Johns Hopkins Medical Institutes]

{{Digestive system diseases}}
[[Category:Inflammations]]
[[Category:Colitis]]
[[Category:2Fix]]