View source for Mitral valve replacement

'''Mitral valve replacement''' is a [[cardiac surgery]] procedure in which a patient’s [[mitral valve]] is replaced by a different valve. Mitral valve replacement is typically performed [[Robotic surgery|robotically]] or manually, when the valve becomes too tight ([[mitral valve stenosis]]) for blood to flow into the left [[ventricle (heart)|ventricle]], or too loose ([[mitral valve regurgitation]]) in which case blood can leak into the left [[atrium (heart)|atrium]] and back up into the [[lung]]<ref name="society1">The Society 1</ref>.

A mitral valve replacement/repair is performed to treat severe cases of [[mitral valve prolapse]], [[heart valve stenosis]], or other valvular diseases.<ref name="BCM Para 1">BCM Para 1</ref> Since a mitral valve replacement is an [[open heart]] surgical procedure, it requires placing the patient on [[cardiopulmonary bypass]] to stop blood flow through the [[heart]] when it is opened up<ref name="society1">The Society 1</ref>.


==Options==
Some surgeons will first recommend repairing the valve instead of replacement, but if the patient is not a good candidate, for the repair, then they must replace the valve instead.<ref>Maryland Para 1</ref>

Many mitral valves can be repaired, especially if the leak is due to wear and tear. When the valve is too damaged to repair, the valve must be replaced with an artificial valve<ref name="sundt2">Sundt 2</ref>.  There are some advantages to repairing a mitral valve versus replacing it. Some of these advantages are; a lower mortality at the time of operation (1-2% for repair versus 6-8% for replacement), a significantly lower risk of [[stroke]], and a lower rate of infection, improved long-term survival with mitral valve repair. Patients who receive a valve repair stay on the same [[survival curve]] as the normal population. After mitral valve repair, [[blood thinner]]s are not required, in contrast to the life-long requirement for blood thinners after mechanical mitral valve replacement<ref name="university1">University 1</ref>.

==Non-Surgical Options==
Most patients can endure surgery without complications; however, there are some whose heart functions are too weak to withstand surgery. Non-surgical approaches to treat heart valve disease without surgery are divided into three categories: Clinical Practice treatment (this is used in every day clinical practice), Investigational treatment (current clinical studies that are underway), Early Development treatment (early stages of investigation).<ref>Heart Para 3</ref>

==Types of Valves==
There are two primary types of artificial mitral valves -- a metal or mechanical valve and a tissue valve or biological valve.<ref name="marylandpara2">Maryland Para 2</ref> The mechanical valves are made entirely from metal and [[pyrolytic carbon]] and last a lifetime<ref name="sundt2">Sundt 2</ref>. With this valve, patients are required to take blood-thinning medications to prevent [[thrombus|clot]]ting. The tissue valve is made from animal tissues<ref name="sundt2">Sundt 2</ref>. The tissue valve doesn’t require a patient to take blood thinners, but it only lasts 10 to 15 years.<ref name="marylandpara2"/>
The choice of which type to use should be made by the patient and his doctors taking the following into consideration: patient's age, medical condition, preferences with medication, and lifestyle.<ref name="sundt3">Sundt 3</ref>

==Details of the procedure==
A mitral valve replacement procedure is performed under [[general anesthesia]], which will keep the patient asleep during the whole surgery.<ref name="BCM Para 1"/>  The preferred method is to first make an incision under the left [[breast]] rather than through the [[breastbone]] in the front of the [[chest]], to get to the heart. After the heart is exposed, blood must be rerouted to a [[heart-lung machine]] (cardiopulmonary bypass)<ref name="bcm1">BCM 1</ref>. An incision is made in the left atrium to expose the mitral valve.  The valve is then replaced with either a biological or mechanical valve. Then after the functioning of the new valve is tested and confirmed, the heart is then closed with [[surgical suture|suture]]s<ref name="bcm1">BCM 1</ref>.  The patient is then taken off the cardiopulmonary bypass and blood is allowed to flow into the [[coronary arteries]].  If the heart does not beat on its own, an electric shock is used to start it. Then the chest is closed up<ref name="bcm1">BCM 1</ref>..

==Risks==
With mitral valve replacement surgery, there are risks such as bleeding, infection, or a complicated reaction to anesthesia<ref name="bcm2">BCM 2</ref>. Each risk is determined best with each patients own [[cardiologist]] and cardiothoracic surgeon.  They will better know each individuals medical history and conditions. Risks depend on a patient’s age, general condition, specific medical conditions, and heart function<ref name="sundt3">Sundt 3</ref>.

==Postoperative Complications/ Risks==
A common postoperative complication with mitral valve surgery in a study involving 99 patients who had surgery for mitral regurgitation from January 1990 to June 1996 is [[atrial fibrillation]].  This occurred in 32% of patients.  A common pulmonary complication is congestion necessitating prolonged use of [[oxygen]].  Other patients required prolonged ventilation of longer than 24 hours for conditions like [[pulmonary edema]], [[ARDS]], and pulmonary thromboemboli<ref name="hurley1">Hurley 1</ref>.  Nine patients had [[renal failure]] with six of them dying within 30 days after their operation.  Five patients had permanent strokes, and nine patients were readmitted to the hospital within 30 days of their discharge<ref name="hurley1">Hurley 1</ref>.

==Effectiveness==
In a clinical study done of 99 patients who had mitral valve surgery for regurgitation from January 1990 to June 1996, long-term and short-term outcomes were evaluated. These evaluations included; [[mortality rate]], clinical complications, readmissions, valve deterioration, reoperation, and health perception.  Overall mortality was 4%, which included 3 operative deaths and 4 late deaths. Overall 5-year survival rate was 92%<ref name="hurley1">Hurley 1</ref>.

==Condition after mitral valve replacement==
After the surgery the patient is taken to a post-operative intensive care unit for monitoring. A [[medical ventilator|respirator]] may be required for the first few hours or days after surgery. After a day, the patient should be able to sit up in bed. After two days, the patient may be taken out of the intensive care unit.  Patients are usually discharged after about seven to ten days<ref name="bcm1">BCM 1</ref>.  If the mitral valve replacement is successful, patients can expect to return to their regular condition or even better.  Patients who have biological valve are prescribed blood thinners (Anticoagulation) with Coumadin for 6 weeks to 3 months postoperative, while patients with mechanical valves are prescribed blood thinners for the rest of their lives.  These blood thinners are taken to prevent blood clots that can move to other parts of your body and cause serious medical problems, such as a [[heart attack]]. Blood thinners will not dissolve a blood clot but they prevent other clots from forming or prevent clots from becoming larger. <ref>Heart Disease 1</ref> Once the patient’s wounds are healed they should have few, if any, restrictions from daily activities<ref name="sundt1">Sundt 1</ref>.  Patients are advised to walk or undertake other physical activities gradually to regain strength.  Patients who have physically demanding jobs will have to wait a little longer than those who don’t.  Patients are also restricted from driving a car for six weeks after the surgery<ref name="mitral2">Mitral 2</ref>.  Once a person has a mitral valve procedure, they are required to have prophylactic [[antibiotics]] as a preventative measure against infection whenever they have dental work done<ref name="sundt4">Sundt 4</ref>.

Depending on the method of surgery, some scarring will occur.  If the breastbone is divided, the patient will have a long scar along the breast bone.  If the heart is accessed from under the left breast there will be a smaller scar in the spot<ref name="mitral2">Mitral 2</ref>.

==See also==
* [[Mitral regurgitation]]
* [[Artificial heart valve]]
* [[Mitral stenosis]]
* [[Heart-lung machine]]

==References==
{{reflist}}

==External links==
*[http://www.debakeydepartmentofsurgery.org/home/content.cfm?proc_name=mitral+valve+repair+replacement&content_id=274 BCM: The Michael E DeBakey Department of Surgery. Mitral Valve Repair/ Replacement. n.d. 29 Apr. 2007]
*[http://www.ecu.edu/dhs/news/newsstory.cfm?ID=16 "FDA approves second clinical trial for robotic heart surgery." Health Sciences News. 9 Nov. 2000. ECU Division of Health Sciences. 2 May 2007]
*[http://www.nlm.nih.gov/medlineplus/ency/article/000180.htm Gandelman, Glenn. "Medical encyclopedia." Medline Plus. n.d. 3 May 2007]
*[http://www.webmd.com/heart-disease/warfarin-other-blood-thinners?page=1 "Heart Disease: Warfarin and Other Blood Thinners." WebMD. The Cleveland Clinic. 10 May 2007 ]
*[http://www.clevelandclinic.org/heartcenter/pub/guide/percutaneous/percutaneousValve.htm#investigational#investigational Heart and Vascular Institute. ''Heart Valve Disease - Percutaneous Interventions: Non-surgical approaches.'' 2007. 7 May 2007 ]
*[http://www.umm.edu/heart/mitral_repla.html "Mitral Valve Replacement." University of Maryland Medical Center: 1-2. 26 Apr. 2007  ]
*[http://www.graphpad.com/www/book/survive.htm Motulsky, Harvey. ''Intuitive Biostatistics''. Oxford University Press Inc, 1995. 2 May 2007 ]

{{cardiac surgery}}

[[Category:Cardiology]]
[[Category:Valvular heart disease]]

[[uk:Протезування мітрального клапану]]
[[Category:2Fix]]