View source for Picotamide

{{drugbox
| IUPAC_name        = 4-methoxy-''N,N'''-bis(pyridin-3-ylmethyl)isophthalamide
| image             = picotamide.png
| CAS_number        = 
| ATC_prefix        = B01
| ATC_suffix        = AC03 
| PubChem           = 4814
| DrugBank          = 
| C=21|H=20|N=4|O=3
| molecular_weight  = 376.409 g/mol
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category=  
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = 
}}

'''Picotamide''' is a [[platelet aggregation inhibitor]]. It works by inhibiting the enzyme [[thromboxane-A synthase]] and by modifying cellular responses to activation of the [[thromboxane receptor]].<ref>{{cite journal|doi=10.1016/S0014-2999(98)00467-1|pmid=9754941|title=Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes|first5=A|last5=Corsini|first4=R|last4=Fumagalli|first3=C|last3=Casagrande|first2=P|year=1998|last2=Quarato|last1=Ratti|first1=S|journal=European Journal of Pharmacology|volume=355|issue=1|pages=77}}</ref>

==References==
{{reflist}}

{{Antithrombotics}}

[[Category:Antiplatelet drugs]]
[[Category:Pyridines]]
[[Category:Benzamides]]
[[Category:Phenol ethers]]


{{blood-drug-stub}}

[[pt:Picotamida]]
[[Category:2Fix]]