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[[File:Linezolid-from-xtal-2008-3D-balls.png|thumb|right|250px|Ball-and-stick model of linezolid]]
'''[[Linezolid]]''' is a synthetic [[antibiotic]] used for the treatment of serious [[infection]]s caused by [[Gram-positive bacteria]] that are [[antibiotic resistance|resistant]] to several other antibiotics. A member of the [[oxazolidinone]] class of drugs, linezolid is active against most Gram-positive bacteria that cause disease, including [[Streptococcus|streptococci]], [[vancomycin-resistant enterococcus|vancomycin-resistant enterococci]], and [[methicillin-resistant Staphylococcus aureus|methicillin-resistant ''Staphylococcus aureus'']]. The main [[indication (medicine)|indications]] of linezolid are infections of the [[skin]] and [[soft tissue]]s and [[pneumonia]] (particularly [[hospital-acquired pneumonia]]), although [[off-label use]] for a variety of other infections is becoming popular. Discovered in the late 1980s and first approved for use in 2000, linezolid was the first commercially available oxazolidinone antibiotic. As of 2009, it is the only marketed oxazolidinone, although others are in development. As a [[protein synthesis inhibitor]], it stops the growth of bacteria by disrupting their [[protein biosynthesis|production of proteins]]. Resistance to linezolid has remained very low since it was first detected in 1999, although it may be increasing. When administered for short periods, linezolid is a relatively safe drug; it can be used in patients of all ages and in people with [[liver disease]] or [[renal failure|poor kidney function]]. ('''[[Linezolid|more...]]''')

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'''[[WP:FA|Featured]] pharmacology articles:'''

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[[Category:2Fix]]