View source for Roth's spot

'''Roth's spots''' are [[retina]]l [[hemorrhage]]s with white or pale centers composed of [[coagulate]]d [[fibrin]]. They are typically observed via [[fundoscopy]] (using an [[ophthalmoscope]] to view inside the [[eye]]) or slit lamp exam.

They are usually caused by immune complex mediated vasculitis often resulting from bacterial [[endocarditis]].
Roth's spots may be observed in [[leukemia]], [[diabetes]], subacute bacterial [[endocarditis]], [[pernicious anaemia]], [[ischemia|ischemic events]], and rarely in HIV retinopathy.

Roth's spots are named after [[Moritz Roth]].<ref>{{WhoNamedIt|synd|2684}}</ref><ref>M. Roth. Über Netzhautaffectionen bei Wundfiebern. I. Die embolische Panophthalmitis. Deutsche Zeitschrift für Chirurgie, Leipzig, 1872, 1: 471-484.</ref>

==See also==
*[[Osler's nodes]]
*[[Janeway lesion]]

==References==
{{reflist}}

==External links==
* [http://www.nature.com/eye/journal/v19/n5/fig_tab/6701530f2.html Image at Nature.com]

{{Eponymous medical signs for eyes and ears}}
{{Eponymous medical signs for cardiovascular system}}

[[Category:Ophthalmology]]


{{med-sign-stub}}

[[es:Manchas de Roth]]
[[pl:Plamki Rotha]]
[[Category:2Fix]]