View source for Secoisolariciresinol diglucoside

{{chembox
| Name = 
| ImageFile = sdg_composition.png
| ImageSize = 200px
| ImageName = Chemical structure of SDG
| IUPACName = 
| OtherNames = SDG<!-- <br> -->
|Section1= {{Chembox Identifiers
| CASNo = 
| CASNo_Ref = 
| CASOther = 
| PubChem = 
| SMILES = 
| InChI = 
| MeSHName = 
}}
|Section2= {{Chembox Properties
| Formula = C<sub>32</sub>H<sub>46</sub>O<sub>16</sub>
| MolarMass = 686.7g/mol
| ExactMass = u
| Appearance = 
| Density = 
| MeltingPt = <!-- °C -->
| BoilingPt = <!-- °C -->
| Solubility = 
}}
}}
'''Secoisolariciresinol diglycoside''' (SDG)  is an [[anti-oxidant]] [[phytochemical]] present in [[flax]], [[sunflower]], [[sesame]], and [[pumpkin]] seeds. It is a precursor of [[mammal]] [[lignan]]s and a [[phytoestrogen]].

Animal studies have shown SDG can prevent the development of [[atherosclerosis]] and [[diabetes]], and has beneficial modifying effect on [[blood]] and [[cholesterol]] levels. It may play very different role in the people with the already existent cancer. In the Grade IV histology group of adult patients diagnosed with malignant glioma, high intake of secoisolariciresinol (for highest tertile compared to lowest tertile, in all cases) was associated with poorer survival.<ref>Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma BMC Cancer 2010, 10:215doi:10.1186/1471-2407-10-215 http://www.biomedcentral.com/1471-2407/10/215</ref>

Secoisolariciresinol diglucoside can be isolated from de-fatted ([[hexane]] [[solvent extraction|extraction]]) [[flaxseed]] by [[solvent extraction|extraction]] of the lignan [[polymer]] precursor with a water/[[acetone]] mixture, followed by acetone removal and alkaline hydrolysis.<ref>{{US patent|6806356}} ''Process for recovering secoisolariciresinol diglycoside from de-fatted flaxseed''.</ref>

==References==
<references />

==External links==
*[http://www.gaiaresearch.co.za/flaxseed.html Flaxseed Lignans & the Immune System]
*[http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/sec_0297.shtml pdrhealth.com]

{{Lignan}}

[[Category:Antioxidants]]
[[Category:Lignans]]
[[Category:Glycosides]]
[[Category:Phenols]]
[[Category:Phenol ethers]]

[[ru:Диглюкозид секоизоларициресинола]]
[[Category:2Fix]]