Difference between revisions of "Tasosartan"

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Tasosartan
File:Tasosartan.png
Systematic (IUPAC) name
2,4-dimethyl-8-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
Identifiers
ATC code C09CA05 (WHO)
PubChem CID 60919
Chemical data
Formula C23H21N7O
Molar mass 411.459 g/mol[[Script error: No such module "String".]]
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Tasosartan is an angiotensin II receptor antagonist.

It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.[1][2]

References

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hu:Tasosartan pt:Tasosartan
  1. Atkinson AJ; et al. (2007). Principles of clinical pharmacology. Amsterdam: Elsevier. p. 515. ISBN 0-12-369417-5. 
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