Difference between revisions of "Clofoctol"
From Self-sufficiency
m (Adding category Category:Organochlorides (using HotCat)) |
m (1 revision) |
(No difference)
| |
Latest revision as of 10:23, 20 September 2010
| File:Clofoctol.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
2-[(2,4-dichlorophenyl)methyl]- 4-(2,4,4-trimethylpentan-2-yl)phenol | |
| Clinical data | |
| Routes of administration | Rectal (suppository)[1][2] |
| Pharmacokinetic data | |
| Bioavailability | 98%[1] |
| Metabolism | Hepatic glucuronidation[1] |
| Excretion | Biliary[1] |
| Identifiers | |
| CAS Number | 37693-01-9 |
| ATC code | J01XX03 (WHO) |
| PubChem | CID 2799 |
| ChemSpider | 2697 |
| Chemical data | |
| Formula | C21H26Cl2O |
| Molar mass | 365.336 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria.[1][2]
It is marketed in France under the trade name Octoplus and in Italy as Gramplus.
It is only functional against Gram-positive bacteria.[3]
It penetrates into human lung tissue.[4]
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
| 50px | This systemic antibacterial-related article is a stub. You can help ssf by expanding it. |
- ↑ 1.0 1.1 1.2 1.3 1.4 "Gramplus" (in Italian). Studio Medico Torrino. July 25, 2007. Retrieved 2007-08-10.
- ↑ 2.0 2.1 "Clofoctol" (in French). BIAM. July 16, 1999. Retrieved 2007-08-10.
- ↑ Combe J, Simonnet F, Yablonsky F, Simonnet G (1980). "[Clofoctol binding by the bacteria (author's transl)]". J Pharmacol (in French). 11 (4): 411–25. PMID 6782374.
- ↑ Danesi R, Gasperini M, Senesi S, Freer G, Angeletti CA, Del Tacca M (1988). "A pharmacokinetic study of clofoctol in human plasma and lung tissue by using a microbiological assay". Drugs Exp Clin Res. 14 (1): 39–43. PMID 3391105.
Categories:
- Pages with script errors
- Pages with broken file links
- Infobox drug tracked parameters
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Antibiotic stubs
- 2Fix
- Antibiotics
- Phenols
- Organochlorides
- CS1 maint: Unrecognized language
- CS1 maint: Multiple names: authors list
