Difference between revisions of "Carbonyl cyanide m-chlorophenyl hydrazone"

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Latest revision as of 10:26, 20 September 2010

Carbonyl cyanide m-chlorophenyl hydrazone
File:Carbonyl cyanide m-chlorophenyl hydrazone.svg
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 555-60-2 YesY
PubChem 2603
ChemSpider 2504
MeSH CCCP
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InChI key UGTJLJZQQFGTJD-UHFFFAOYAQ
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C9H5ClN4
Molar mass 204.62 g mol−1
 YesY (what is this?)  (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Carbonyl cyanide m-chlorophenyl hydrazone (CCCP), is a chemical inhibitor of oxidative phosphorylation. It is a nitrile, hydrazone and ionophore. In general, CCCP causes the gradual destruction of living cells and death of the organism.[1] [2] The CCCP affects the protein synthesis reactions in seedling mitochondria;[3] the mechanisms of action of CCCP are under intensive study, see [4] and references therein.

CCCP causes an uncoupling of the proton gradient that is established during the normal activity of electron carriers in the electron transport chain. The chemical acts essentially as an ionophore and reduces the ability of ATPsynthase to function optimally.



References

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it:Carbonil cianuro m-clorofenil idrazone

ja:カルボニルシアニド-m-クロロフェニルヒドラゾン

pt:Carbonilcianeto m-clorofenil-hidrazona
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