Fluocinolone acetonide
From Self-sufficiency
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| File:Fluocinolone acetonide.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one | |
| Clinical data | |
| Pregnancy category |
|
| Routes of administration | Topical |
| Pharmacokinetic data | |
| Metabolism | Hepatic, CYP3A4-mediated |
| Biological half-life | 1.3 to 1.7 hours |
| Identifiers | |
| CAS Number | 67-73-2 |
| ATC code | C05AA10 (WHO) D07AC04 S01BA15 S02BA08 |
| PubChem | CID 6215 |
| DrugBank | APRD00977 |
| Chemical data | |
| Formula | C24H30F2O6 |
| Molar mass | 452.488 g/mol[[Script error: No such module "String".]] |
| (verify) | |
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.
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| 40px | This dermatologic drug article is a stub. You can help ssf by expanding it. |
it:Fluocinolone acetonide hu:Fluocinolon-acetonid pl:Fluocynolon uk:Флуоцинолон ацетонід
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