Reversine

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Reversine
File:Reversine.png
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 656820-32-5
PubChem 210332
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style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C21H27N7O
Molar mass 393.48538
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.

References

  • Chen S, Zhang Q, Wu X, Schultz PG, Ding S (2004) Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc., 126(2):410–411. [PMID 14719906]
  • Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG (2007) Reversine increases the plasticity of lineage-committed mammalian cells. Proc Natl Acad Sci U S A. 104(25):10482-7. [PMID 17566101]

External links


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