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From Self-sufficiency
- Rifampicin inhibits DNA-dependent [[RNA polymerase]] in bacterial cells by binding its beta-subunit ...cannot stop the elongation of mRNA once binding to the template-strand of DNA has been initiated.<ref name="Hardman">Hardman, Joel G., Lee E. Limbird, an18 KB (2,471 words) - 16:43, 27 September 2010
- ...clo-GTP from the chain, which results in inhibition of further activity of DNA polymerase. Acyclo-GTP is fairly rapidly [[metabolism|metabolised]] within ...ent viral thymidine kinase; and mutations to viral thymidine kinase and/or DNA polymerase, altering substrate sensitivity.<ref name="Martindale34">Sweetma14 KB (1,878 words) - 16:44, 27 September 2010
- ...ester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. {{Antivirals}}9 KB (1,248 words) - 16:44, 27 September 2010
- Ribavirin is active against a number of [[DNA]] and [[RNA]] [[virus]]es. It is a member of the [[nucleoside]] antimetabol ...HIV antiviral didanosine (ddI, Videx). Other interactions with nucleoside antivirals for HIV should be considered when HIV/AIDS patients use ribavirin to treat23 KB (3,222 words) - 16:45, 27 September 2010