Cytoprotection
Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents.[1]
A gastric cytoprotectant is any medication that combats ulcers not by reducing gastric acid but by increasing mucosal protection.[2] Examples of gastric cyctoprotective agents include prostaglandins which protect the stomach mucosa against injury. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins and thereby make the stomach more susceptible in injury.[3] Gastric cytoprotective drugs include carbenoxolone, deglycyrrhizinised liquorice, sucralfate (aluminium hydroxide and sulphated sucrose), misoprostol (a prostaglandin analogue) and bismuth chelate (tri-potassium di-citrato bismuthate).
References
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- ↑ "MeSH Heading: Cytoprotection". Medical Subject Headings. United States National Library of Medicine.
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