Template:PBB/3757
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(PDB: rendering of the N-terminal domain)
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Potassium voltage-gated channel, subfamily H (eag-related), member 2
250px
PDB
rendering of the N-terminal domain based on 1byw.
Available structures
PDB
1byw
,
1ujl
Identifiers
Symbols
KCNH2
; ERG1; HERG; HERG1; Kv11.1; LQT2; SQT1
External IDs
OMIM
:
152427
MGI
:
1341722
HomoloGene
:
201
IUPHAR
:
K
v
11.1
GeneCards
:
KCNH2 Gene
Gene Ontology
Molecular function
•
two-component sensor activity
•
ion channel activity
•
voltage-gated potassium channel activity
•
delayed rectifier potassium channel activity
•
potassium ion binding
Cellular component
•
membrane fraction
•
nuclear envelope
•
cytoplasm
•
plasma membrane
•
voltage-gated potassium channel complex
•
membrane
•
integral to membrane
Biological process
•
two-component signal transduction system (phosphorelay)
•
regulation of transcription, DNA-dependent
•
ion transport
•
potassium ion transport
•
muscle contraction
•
sensory perception of sound
•
regulation of heart contraction
Sources:
Amigo
/
EGO
RNA expression pattern
250px
250px
250px
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
3757
16511
Ensembl
ENSG00000055118
ENSMUSG00000038319
UniProt
Q12809
Q53Z09
RefSeq (mRNA)
NM_000238
XM_981382
RefSeq (protein)
NP_000229
XP_986476
Location (UCSC)
Chr 7:
150.27 - 150.31 Mb
Chr 5:
23.83 - 23.86 Mb
PubMed
search
[1]
[2]
Categories
:
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Human proteins
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