Estratetraenol

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Estratetraenol
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Systematic (IUPAC) name
(8S,9S,13R,14S)-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-ol
Identifiers
CAS Number 1150-90-9
ATC code none
PubChem CID 101988
Chemical data
Formula C18H22O
Molar mass 254.366 g/mol[[Script error: No such module "String".]]
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Estratetraenol, also known as estra-1,3,5(10),16-tetraen-3-ol, is a chemical compound produced by women[1] that has been described as having pheromone-like activities in primates[2], including humans.[3][4][5][6] It is derivative of the sex hormone estradiol, an estrogen, yet has no known estrogenic effects.

References

  1. Thysen B, Elliott WH, Katzman PA. Identification of estra-1,3,5(10),16-tetraen-3-ol (estratetraenol) from the urine of pregnant women. Steroids. 1968 Jan;11(1):73-87. PMID 4295975
  2. Laska M, Wieser A, Salazar LT. Sex-specific differences in olfactory sensitivity for putative human pheromones in nonhuman primates. Journal of Comparative Psychology. 2006 May;120(2):106-12. PMID 16719588
  3. Jacob S, Hayreh DJ, McClintock MK. Context-dependent effects of steroid chemosignals on human physiology and mood. Physiology and Behaviour. 2001 Sep 1-15;74(1-2):15-27. PMID 11564447
  4. Savic I, Berglund H, Gulyas B, Roland P. Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans. Neuron. 2001 Aug 30;31(4):661-8. PMID 11545724
  5. Berglund H, Lindström P, Savic I. Brain response to putative pheromones in lesbian women. Proceedings of the National Academy of Sciences USA. 2006 May 23;103(21):8269-74. PMID 16705035
  6. Berglund H, Lindström P, Dhejne-Helmy C, Savic I. Male-to-female transsexuals show sex-atypical hypothalamus activation when smelling odorous steroids. Cerebral Cortex. 2008 Aug;18(8):1900-8. PMID 18056697


See also