Alphamethylacetylfentanyl

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Alphamethylacetylfentanyl
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Systematic (IUPAC) name
N-phenyl-N-[1-(1-phenylpropan-2-yl)-4-piperidyl]acetamide
Legal status
Legal status
Identifiers
CAS Number 101860-00-8
ATC code none
PubChem CID 62307
ChemSpider 56102
Synonyms α-methylacetylfentanyl, acetyl-α-methylfentanyl
Chemical data
Formula C22H28N2O
Molar mass 336.471 g/mol[[Script error: No such module "String".]]
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α-methylacetylfentanyl is an opioid analgesic that is an analogue of fentanyl.

α-methylacetylfentanyl was sold briefly on the black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. [1] α-methylacetylfentanyl is made with the same synthetic route as α-methylfentanyl, but by substituting the relatively common acetic anhydride for the more difficult to obtain chemical propionic anhydride in the synthesis.

α-methylacetylfentanyl has similar effects to fentanyl. Side effects of fentanyl analogues are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression which can be life-threatenng.

References

  1. Henderson GL. Designer Drugs: Past History and Future Prospects. Journal of Forensic Sciences 1988; 33(2):569-575