OR3A2

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Olfactory receptor, family 3, subfamily A, member 2
Identifiers
Symbols	OR3A2; OLFRA04; OR17-14; OR17-228; OR228
External IDs	MGI: 3030244 HomoloGene: 68262 GeneCards: OR3A2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • integral to plasma membrane • membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4995	258702
Ensembl	ENSG00000205813	ENSMUSG00000063116
UniProt	P47893	n/a
RefSeq (mRNA)	NM_002551	NM_146707
RefSeq (protein)	NP_002542	NP_666918
Location (UCSC)	Chr 17: 3.13 - 3.24 Mb	Chr 11: 74.15 - 74.15 Mb
PubMed search	[1]	[2]

Olfactory receptor 3A2 is a protein that in humans is encoded by the OR3A2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Ben-Arie N, Lancet D, Taylor C; et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum. Mol. Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rouquier S, Taviaux S, Trask BJ; et al. (1998). "Distribution of olfactory receptor genes in the human genome". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR3A2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.