OR5L1
| edit |
| Olfactory receptor, family 5, subfamily L, member 1 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | OR5L1; OR11-151; OST262 | ||||||||||||
| External IDs | MGI: 3030991 HomoloGene: 17402 GeneCards: OR5L1 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 219437 | 258846 | |||||||||||
| Ensembl | ENSG00000186117 | ENSMUSG00000075143 | |||||||||||
| UniProt | Q8NGL2 | n/a | |||||||||||
| RefSeq (mRNA) | NM_001004738 | NM_146849 | |||||||||||
| RefSeq (protein) | NP_001004738 | NP_667060 | |||||||||||
| Location (UCSC) | Chr 11: 55.34 - 55.34 Mb | Chr 2: 87.76 - 87.76 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
Olfactory receptor 5L1 is a protein that in humans is encoded by the OR5L1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.
Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
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<references />, or <references group="..." />Further reading
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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