Template:PBB/6010

Rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)
250px Sensory rhodopsin II (rainbow colored) embedded in a lipid bilayer (heads red and tails blue) with Transducin below it. Gtα is colored red, Gtβ blue, and Gtγ yellow. There is a bound GDP molecule in the Gtα-subunit and a bound retinal (black) in the rhodopsin. The N-terminus terminus of rhodopsin is red and the C-terminus blue. Presumed anchoring of transducin to the membrane has been drawn in black.
Available structures PDB 1eds, 1edx, 1f88, 1gzm, 1hzx, 1jfp, 1l9h, 1ln6, 1u19, 2g87, 2hpy, 2i35, 2i36, 2i37
Identifiers
Symbols	RHO; MGC138309; MGC138311; OPN2; RP4
External IDs	OMIM: 180380 MGI: 97914 HomoloGene: 68068 GeneCards: RHO Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity Cellular component • photoreceptor outer segment • plasma membrane • integral to plasma membrane Biological process • G-protein coupled receptor protein signaling pathway • visual perception • phototransduction, visible light • rhodopsin mediated signaling • protein-chromophore linkage • response to stimulus Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6010	212541
Ensembl	ENSG00000163914	ENSMUSG00000030324
UniProt	P08100	Q8K0D8
RefSeq (mRNA)	NM_000539	NM_145383
RefSeq (protein)	NP_000530	NP_663358
Location (UCSC)	Chr 3: 130.73 - 130.74 Mb	Chr 6: 115.9 - 115.9 Mb
PubMed search	[1]	[2]