Foster Kennedy syndrome

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Foster Kennedy syndrome
Classification and external resources
ICD-9 377.04
DiseasesDB 31967

Foster Kennedy syndrome (also known as Gowers-Paton-Kennedy syndrome, Kennedy's phenomenon or Kennedy's syndrome) refers to a constellation of findings associated with tumors of the frontal lobe. [1]

Although "Foster Kennedy syndrome" is equated with "Kennedy syndrome",[2] it should not be confused with Kennedy disease, which is named for W. R. Kennedy.

Pseudo-Foster Kennedy syndrome is defined as one-sided optic atrophy with papilledema in the other eye but with the absence of a mass.[3]

Presentation

The syndrome is defined as the following changes:

  • optic atrophy
  • papilledema in the opposite eye
  • Central scotoma (loss of vision in the middle of the visual fields) in the same eye
  • anosmia (loss of smell) on the same side

This syndrome is due to optic nerve compression, olfactory nerve compression, and increased intracranial pressure (ICP) secondary to a mass (such as meningioma or plasmacytoma, usually an olfactory groove meningioma).[4][5] There are other symptoms present in some cases such as nausea and vomiting, memory loss and emotional lability (i.e. frontal lobe signs).[5]

History

The syndrome was first extensively noted by Robert Foster Kennedy in 1911, a British neurologist, who spent most of his career working in the United States of America.[6] However, the first mention of the syndrome came from a William Gowers in 1893. Schultz-Zehden described the symptoms again in 1905. A later description was written by Wilhelm Uhthoff in 1915.[7]

Treatment and prognosis

The treatment, and therefore prognosis, varies depending upon the underlying tumour.[5]

References

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de:Foster Kennedy-Syndrom

it:Sindrome di Foster-Kennedy

pl:Zespół Fostera Kennedy'ego
  1. Kennedy syndrome at Dorland's Medical Dictionary
  2. Foster Kennedy syndrome at Dorland's Medical Dictionary
  3. Bansal S, Dabbs T, Long V (2008). "Pseudo-Foster Kennedy Syndrome due to unilateral optic nerve hypoplasia: a case report". J Med Case Reports. 2: 86. doi:10.1186/1752-1947-2-86. PMC 2278154Freely accessible. PMID 18348732. Retrieved 2008-08-13. 
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  5. 5.0 5.1 5.2 Willacy, Hayley. "Foster Kennedy syndrome". Retrieved 2008-08-13. 
  6. Thorofare, NJ (1911). Kennedy F; Retrobulbar neuritis as an exact diagnostic sign of certain tumors and abscesses in the frontal lobe. American Journal of the Medical Sciences. 
  7. "Kennedy's syndrome". Retrieved 2008-08-13.