Quassin

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Quassin
(+)-Quassin
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 76-78-8
PubChem 10971
EC number 200-985-9
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InChI key IOSXSVZRTUWBHC-LBTVDEKVBB
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C22H28O6
Molar mass 388.45 g mol−1
Appearance White crystalline substance
Melting point

200-222 °C

Boiling point

586 °C

Solubility in water Insoluble
Vapor pressure 13 mmHg (@25 °C)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Quassin is a white bitter, crystalline substance extracted from the quassia tree. It is the bitterest substance found in nature with a bitter threshold of 0.08 ppm and it is 50 times more bitter than quinine.[1]

Quassin is used as a medicine in traditional Chinese medicine.

Extracts of the Bitter tree (or bitter wood) (Quassia amara L. or Picrasma excelsa) are also used as additives in soft drinks.[1]

Although its skeleton possesses 20 carbon atoms, quassin is not a diterpene but rather a triterpene lactone, which derives from euphol by loss of 10 carbon atoms including C4.

References

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fr:Quassine
  1. 1.0 1.1 Scientific Committee on Food Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002). SCF/CS/FLAV/FLAVOUR/29 Final