Optochin
From Self-sufficiency
| Optochin | |
|---|---|
| File:Optochin.png | |
| (4β,8α,9R)-6'-Ethoxy-10,11-dihydrocinchonan-9-ol | |
| Other names Ethylhydrocupreine | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 522-60-1 |
| PubChem | 71542 |
| MeSH | Optochin |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C21H28N2O2 |
| Molar mass | 340.46 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Optochin (or ethylhydrocupreine) is a chemical used in cell culture techniques for the presumptive identification of Streptococcus pneumoniae, which is optochin-sensitive, from other α-haemolytic streptococci such as Streptococcus viridans which are resistant.
The growth of Bacteria that are optochin sensitive will be inhibited around an optochin disc, while the growth of bacteria that are optochin resistant will not be affected.
Resistance
Strains of Streptococcus pneumoniae have been found to be resistant to optochin in laboratory testing.[1]
References
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<references />, or <references group="..." />- ↑ Pikis A, Campos JM, Rodriguez WJ, Keith JM (2001), "Optochin resistance in Streptococcus pneumoniae: mechanism, significance, and clinical implications", Journal of Infectious Diseases, 184 (5): 582–590, doi:10.1086/322803, PMID 11474432
