Cirazoline
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| Cirazoline | |
|---|---|
| File:Cirazoline.png | |
| 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 59939-16-1 |
| PubChem | 2765 |
| ChemSpider | 2663 |
| MeSH | cirazoline |
| IUPHAR ligand | 515 |
| SMILES | Script error: No such module "collapsible list". |
| InChI | Script error: No such module "collapsible list". |
| InChI key | YAORIDZYZDUZCM-UHFFFAOYAV |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C13H16N2O |
| Molar mass | 216.279 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Cirazoline is a nonselective agonist of the alpha-1 adrenergic receptor (α1-AR), and an antagonist to the alpha-2 adrenergic receptor[1]. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent[1].
Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of alpha 1-adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain[2].
References
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