Formononetin

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Formononetin
File:Formononetin.svg
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 485-72-3 YesY
PubChem 5280378
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Beilstein Reference 237979
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C16H12O4
Molar mass 268.26 g/mol
Exact mass 268.073559
 YesY (what is this?)  (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Formononetin is an O-methylated isoflavone. It is found in a number of plants and herbs like the red clover[1].

Metabolism

The enzyme 4'-methoxyisoflavone 2'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce 2'-hydroxyformononetin, NADP+ and H2O.

The enzyme Isoflavone 3'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce calycosin (3'-hydroxyformononetin), NADP+ and H2O.

Glycosides

Ononin is the 7-O-glucoside of formononetin.

References

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  1. Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor, S. Medjakovica and A. Jungbauer, 2007