Progression-free survival
Progression-free survival or PFS is a term used to describe the length of time during and after medication or treatment during which the disease being treated (usually cancer) does not get worse. It is sometimes used as a metric to study health of a person with a disease to try to determine how well a new treatment is working.[1]
It is a metric frequently used by the UK NICE to evaluate the cost effectiveness of a cancer treatment.[2] PFS has been postulated by several key opinion leaders in oncology to be a better ("more pure") measure of efficacy in second-line clinical trials as it eliminates potential differential bias from prior or subsequent treatments.[citation needed]
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- ↑ "Progression Free Survival (PFS)" at About.com
- ↑ BMJ 31-Jan-2009 "NICE and the challenge of cancer drugs" p271
