Phlegmasia cerulea dolens
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| Phlegmasia cerulea dolens | |
|---|---|
| Classification and external resources | |
| DiseasesDB | 32484 |
| MedlinePlus | 000200 |
| eMedicine | med/2767 |
Phlegmasia cerulea dolens (literally: painful blue edema) is an uncommon severe form of deep venous thrombosis which results from extensive thrombotic occlusion (blockage by a blood clot) of the major and the collateral veins of an extremity. It is characterized by sudden severe pain, swelling, cyanosis and edema of the affected limb. There is a high risk of massive pulmonary embolism, even under anticoagulation. Foot gangrene may also occur. An underlying malignancy is found in 50% of cases.
This phenomenon was discovered by Jonathan Towne, a vascular surgeon in Milwaukee, who was also the first to report the "white clot syndrome" (Now called HIT= Heparin induced thrombocytopenia). Two of their HIT patients developed Phlegmasia cerulea dolens that went on to become gangrenous[1].
See also
References
- ↑ Heparin-Induced Thrombocytopenia By Theodore E. Warkentin, Andreas Greinacher, Published 2004, ISBN 0824756258
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