Template:PBB/183

Angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
250px Space-filling models of angiotensin I (left) and II (right). From PDB 1N9U and 1N9V.
Identifiers
Symbols	AGT; ANHU; SERPINA8
External IDs	OMIM: 106150 MGI: 87963 HomoloGene: 14 GeneCards: AGT Gene
Gene Ontology Molecular function • serine-type endopeptidase inhibitor activity • hormone activity • type 1 angiotensin receptor binding • type 2 angiotensin receptor binding Cellular component • extracellular region • extracellular space • soluble fraction Biological process • ovarian follicle rupture • blood vessel development • ureteric bud branching • kidney development • angiotensin mediated vasoconstriction during regulation of blood pressure • renal response to blood flow during renin-angiotensin regulation of blood pressure • renin-angiotensin regulation of aldosterone production • angiotensin mediated regulation of renal output • brain renin-angiotensin system • cell-matrix adhesion • cell surface receptor linked signal transduction • cell-cell signaling • female pregnancy • establishment of blood-nerve barrier • blood pressure regulation • negative regulation of cell proliferation • response to cold • extracellular matrix organization and biogenesis • peristalsis • positive regulation of body size • hormone metabolic process • drinking behavior • positive regulation of MAPKKK cascade • negative regulation of neuron apoptosis • positive regulation of fatty acid biosynthetic process • positive regulation of organ size • astrocyte activation • smooth muscle cell proliferation • smooth muscle cell differentiation Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	183	11606
Ensembl	ENSG00000135744	ENSMUSG00000031980
UniProt	P01019	Q3UTR7
RefSeq (mRNA)	NM_000029	NM_007428
RefSeq (protein)	NP_000020	NP_031454
Location (UCSC)	Chr 1: 228.9 - 228.92 Mb	Chr 8: 127.44 - 127.46 Mb
PubMed search	[1]	[2]