Multicenter Automatic Defibrillator Implantation Trial
From Self-sufficiency
Revision as of 06:38, 10 April 2010 by Citation bot 1 (Talk) (Citation maintenance. [Pu99]Added: doi. You can use this bot yourself! Please report any bugs.)
This article has multiple issues. Please help improve it or discuss these issues on the talk page. |
Multicenter Automatic Defibrillator Implantation Trial and MADIT II[1] are implantable cardioverter defibrillator (or ICD) trials which investigate whether prophylactic ICD therapy in moderately high-risk coronary patients (in addition to conventional therapy) would significantly reduce death compared with patients treated with conventional therapy alone.
The MADIT II trial started in 1997 and ended in 2001 where the safety committee stopped the study because the benefits were already statistically significant.
The study included patients with a prior myocardial infarction and an ejection fraction less than or equal to 30%.
The results were a reduction in mortality of 31% compared to patients receiving conventional therapy alone.
References
- ↑ Moss AJ, Zareba W, Jackson Hall W; et al. (2002). "Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction:". NEJM. 346 (12): 877–83. doi:10.1056/NEJMoa013474. PMID 11907286.
| 40px | This medical treatment-related article is a stub. You can help ssf by expanding it. |
Categories:
- CS1 maint: Explicit use of et al.
- CS1 maint: Multiple names: authors list
- Pages with broken file links
- Articles needing additional references from July 2007
- All articles needing additional references
- Wikipedia articles needing context from May 2009
- Wikipedia introduction cleanup from May 2009
- Orphaned articles from February 2009
- All orphaned articles
- Cardiology
- Medical treatment stubs
- 2Fix
