Sudden unexpected death syndrome
Sudden unexpected death syndrome (SUDS) or Sudden unexpected nocturnal death syndrome (SUNDS) is sudden unexpected death of adolescents and adults during sleep.
Sudden unexplained death syndrome was first noted in 1977 among Hmong refugees in the US.[1][2] The disease was again noted in Singapore, when a retrospective survey of records showed that 230 otherwise healthy Thai men died suddenly of unexplained causes between 1982 and 1990:[3] In the Philippines, SUDS affects 43 per 100,000 per year among young Filipinos. Most of the victims are young males.[4]
Contents
Causes
SUDS has been cloaked in superstition. In Thailand it is particularly believed to be linked to eating rice cakes. Filipinos believe ingesting high levels of carbohydrates just before sleeping causes bangungot.
It has only been recently that the scientific world has begun to understand this syndrome. Victims of bangungot have not been found to have any organic heart diseases or structural heart problems.
However, cardiac activity during SUDS episodes indicates irregular heart rhythms and ventricular fibrillation. The victim survives this episode if the heart's rhythm goes back to normal. Older folks in the Philippines recommend trying wiggling the big toe while experiencing this to snap back.[5]
In the Philippines, most cases of bangungot have been linked with acute hemorrhagic pancreatitis by Filipino medical personnel although the effect might have been due to changes in the pancreas during post-mortem autolysis.[6] In Thailand and Laos, bangungot (or in their term, sudden adult death syndrome) is caused by the Brugada syndrome.[7]
Features
The condition appears to affect primarily young Hmong men from Laos (median age 33)[8] and northeastern Thailand (where the population are mainly of Laotian descent).[9][10] There is a strong hereditary component and the victims tend to die in their sleep.
Pathology
The cause of this syndrome has been theorized to be a form of Brugada Syndrome.[11][12]
It was noted very early on that the disease had the characteristics of a familial cardiac conduction defect (i.e., a problem with the electrical pathways of the heart),[13] and one study has shown evidence for a long-QT syndrome in populations at risk.[14] Thiamine deficiency is common in the risk population because of diet, and is also a cause of a prolonged QT-interval;[15] but proof that inducible ventricular arrhythmia is the cause of this disease came only with the publication of the DEBUT trial in 2003.[16]
Ongoing genetic studies by Spanish electrophysiologist Dr. Josep Brugada Terradellas show that SUDS results from mutations in the cardiac sodium channel gene. This means that it is a chromosomal problem, which is why it runs in families. Therefore doctors say that families who have kin that have suffered from or died of SUDS must see a heart specialist.
Treatment
The only proven way to prevent death is by implantation of a cardiovertor defibrillator. Oral antiarrhythmics such as propranolol are ineffective.[16]
Folk beliefs
This phenomenon is well known among the Hmong people of Laos,[17] who ascribe these deaths to a malign spirit, dab tsuam (pronounced "da cho"), said to take the form of a jealous woman. Hmong men may even go to sleep dressed as women so as to avoid the attentions of this spirit.
Bangungot is depicted in the Philippines as a mythological creature called batibat. This hag-like creature sits on the victim's face or chest so as to immobilize and suffocate him.
Names in different languages
- Bangungot (Philippines)[18]: The term originated from the Tagalog word meaning "to rise and moan in sleep".[6] It is also the Tagalog word for nightmares.
Urom - Bisaya ( Mindanao Philippines )Aga Gomez
See also
References
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<references />, or <references group="..." />Further reading
- Tan, Michael (29 August 2000). "Bangungot". Philippine Daily Inquirer.
- Tan, Michael (1 April 2002). "Revisiting 'bangungot'". Philippine Daily Inquirer.
- Tan, Michael (18 April 2002). "'Bangungot', the sequel". Philippine Daily Inquirer.
- Agence France Presse (8 April 2002). "Sleeping death syndrome terrorises young men". The Borneo Post.
- Center for Disease Control (23 September 1988). "Sudden Unexplained Death Syndrome Among Southeast Asian Refugees". MMWR.
