5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole
From Self-sufficiency
| 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole | |
|---|---|
| File:Dichlororibofuranosylbenzimidazole.png | |
| (2R,3R,4S,5R)-2-(5,6-Dichlorobenzimidazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol | |
| Other names DRB | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 53-85-0 |
| PubChem | 5894 |
| ChemSpider | 5683 |
| SMILES | Script error: No such module "collapsible list". |
| InChI | Script error: No such module "collapsible list". |
| InChI key | XHSQDZXAVJRBMX-DDHJBXDOBF |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C12H12Cl2N2O4 |
| Molar mass | 319.14 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) is a chemical compound that inhibits transcription elongation by RNA Polymerase II. Sensitivity to DRB is dependent on DRB sensitivity inducing factor (DSIF), negative elongation factor (NELF), and positive transcription elongation factor b (P-TEFb). DRB is a nucleoside analog and also inhibits some protein kinases.[1]
References
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