Amonafide
From Self-sufficiency
| File:Amonafide.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
5-amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione | |
| Identifiers | |
| CAS Number | 69408-81-7 |
| ATC code | none |
| PubChem | CID 50515 |
| Chemical data | |
| Formula | C16H17N3O3 |
| Molar mass | 283.325 g/mol[[Script error: No such module "String".]] |
Amonafide (originally AS1413) (INN, trade name Quinamed) is a drug that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and DNA intercalators.
It is being developed as an anti-cancer therapy by Antisoma.[1]
As of 2008[update], it is in Phase III clinical trials. eg In March 2010 it is Phase III trial against secondary acute myeloid leukaemia (AML).[2]
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />External links
- Amonafide entry in the public domain NCI Dictionary of Cancer Terms
- Clinical trials of amonafide at ClinicalTrials.gov
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
| 40px | This antineoplastic or immunomodulatory drug article is a stub. You can help ssf by expanding it. |
- ↑ http://www.genengnews.com/news/bnitem.aspx?name=78979622
- ↑ http://clinicaltrials.gov/ct2/show/NCT00715637 "Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDE Study"
Categories:
- Pages with script errors
- Pages with broken file links
- Infobox drug tracked parameters
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs not assigned an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Articles containing potentially dated statements from 2008
- Articles with invalid date parameter in template
- All articles containing potentially dated statements
- Wikipedia articles incorporating text from the National Cancer Institute Dictionary of Cancer Terms
- Chemotherapeutic agents
- Antineoplastic and immunomodulating drug stubs
- 2Fix
