Benzthiazide

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Benzthiazide
File:Benzthiazide.svg
Systematic (IUPAC) name
6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)- 4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Bioavailability 60 to 70%
Protein binding 30%
Biological half-life 5 to 15 hours
Excretion Renal
Identifiers
CAS Number 91-33-8
ATC code none
PubChem CID 2343
DrugBank DB00562
Chemical data
Formula C15H14ClN3O4S3
Molar mass 431.94 g/mol[[Script error: No such module "String".]]
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Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others[1]) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.

In the United Kingdom, it was also sold in combination with the potassium-sparing diuretic triamterene under the trade name Dytide.[2] The same combination is still available in Switzerland as Dyrenium compositum.[3]

References

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  1. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found. Retrieved on August 29, 2008 through Google Book Search.
  2. "Triamterene and Benzthiazide". PatientUK. 2005. Retrieved 2008-08-29. 
  3. "Dyrenium compositum". Doetsch Grether. n.d. Retrieved 2008-08-29.