Binding coefficient

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In medicinal chemistry and pharmacology, a binding coefficient is a quantity representing the extent to which a chemical compound will bind to a macromolecule.[1][2]

See also

  • Binding constant
  • Partition coefficient

References

  1. Jump up ↑ Schurr JM, Rangel DP, Aragon SR. (2005) "A Contribution to the Theory of Preferential Interaction Coefficients." Biophysical Journal. 89:2258-2276.
  2. Jump up ↑ Shulgin IL, Ruckenstein E (2006) "A Protein Molecule in a Mixed Solvent: The Preferential Binding Parameter via the Kirkwood-Buff Theory." Biophysical Journal. 90:704–707.
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Topics in Medicinal Chemistry
ADME · Bioavailability · Chemogenomics · Drug design · Drug discovery · Enzyme inhibitor · Mechanism of action · New chemical entity · Pharmacodynamics · Pharmacokinetics · Pharmacology · Pharmacophore · Quantitative structure-activity relationship


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