Delphinine
From Self-sufficiency
| Delphinine | |
|---|---|
| File:Delphinine.svg | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 561-07-9 |
| PubChem | 441726 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C33H45NO9 |
| Molar mass | 599.712 |
| Melting point |
197-199 °C |
| style="background: #F8EABA; text-align: center;" colspan="2" | Hazards | |
| Main hazards | Toxic |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Delphinine is a toxic alkaloid (LD50 1.5 mg/kg approx) found in plants from the Delphinium family. It is related in structure and has similar effects to aconitine, acting as an allosteric modulator of voltage gated sodium channels,[1] and producing hypotension, bradycardia and cardiac arrythmia. These effects make it highly poisonous, but in very small doses it has some uses in herbal medicine.[2][3]
References
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Desai HK, Hart BP, Caldwell RW, Jianzhong-Huang JH, Pelletier SW. Certain norditerpenoid alkaloids and their cardiovascular action. Journal of Natural Products. 1998 Jun 26;61(6):743-8. PMID 9644057
- ↑ Díaz JG, Ruiz JG, de La Fuente G. Alkaloids from Delphinium staphisagria. Journal of Natural Products. 2000 Aug;63(8):1136-9. PMID 10978212
