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...the body's μ-opioid endorphin system, delivering pain relief via the same receptor mechanism as morphine.{{citation needed|date=September 2015}} ...uggest it functions to produce withdrawal symptoms by competing for opiate receptor sites within the CNS (a competitive antagonist, not a direct agonist), ther

...D₃]], [[Dopamine D4 receptor|D₄]], and [[Dopamine D5 receptor|D₅]]—and their variants. Dopamine is produced in several areas Via the [[dopamine receptor]]s, D_1-5, dopamine reduces the influence of the indirect pathway

...''The Sympathomimetic Actions of l-Ephedrine and d-Pseudoephedrine: Direct Receptor Activation or Norepinephrine Release?''] Anesth Analg 2003; 97, pp.1239-124 ...ochemistry|steric]] orientation of the [[hydroxyl]] group is important for receptor binding and functional activity.<ref name='Ma'/>

...ts action on the [[D2 receptor|D2 dopamine]] and [[5HT1A|5-HT_1A receptor]]s that can cause some side effects. <ref name="Tfelt">{{cite journal|autho {{Adrenergic agonists}}

...ism of the [[mu receptor]]) but also by acting as a weak but fast-acting [[serotonin]] and [[norepinephrine]] reuptake inhibitor.{{Citation needed|date=April 20 ...linergic properties and is believed be devoid of any activity on dopamine, serotonin or histamin receptors. It is not addictive and tolerance does not develop.<

...antagonist|antagonist]] activity at the [[kappa opioid receptor|κ-opioid receptor]]. Buprenorphine [[hydrochloride]] was first marketed in the 1980s by Recki Suboxone contains buprenorphine as well as the [[opioid]] [[receptor antagonist|antagonist]] [[naloxone]] to deter the abuse of tablets by [[int

...2receptorsimplications for models of schizophrenia](2002)</ref> Other NMDA receptor antagonists include [[ketamine]], [[tiletamine]], and [[dextromethorphan]]. In a similar manner, PCP and analogues also inhibit [[nicotinic acetylcholine receptor]] channels (nAChR). Some analogues have greater potency at nAChR than at NM

...potent [[Kappa Opioid receptor|κ-opioid]] and [[D2 receptor|D₂ receptor]] [[agonist]].<ref name="Zhang2005pabs" /><ref name="Seeman2009">[[#refSeem ...ain a [[Base (chemistry)|basic]] [[nitrogen]]), unlike most known [[opioid receptor]] [[ligand]]s.<ref name="Harding2006p107">[[#refHarding2006|Harding, Schmid

...ssociative]] [[hallucinogen]]. Its [[mechanism of action]] is as an [[NMDA receptor antagonist]], producing effects similar to those of the controlled substan ...o JF, Chang WY, Lin MF, Chen CF | title = Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextrom

...0s by Dr. [[Henri Laborit]] to use in studying the neurotransmitter [[GABA receptor|GABA]].<ref>{{cite journal | author = H. Laborit, J.M. Jouany, J. Gerald, F ...}</ref> and it is a weak agonist at the [[GABA receptor|GABA_B]] receptor, which is [[inhibitory]].<ref name="mechanism" /> GHB is a naturally-occurr