2,4-Dichlorobenzyl alcohol

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2,4-Dichlorobenzyl alcohol
File:Dichlorobenzyl alcohol.png
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 1777-82-8
PubChem 15684
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style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C7H6Cl2O
Molar mass 177.03 g/mol
Melting point

57-60 °C

Boiling point

150 °C (25 mmHg)

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils/Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2mg) and amylmetacresol (600μg) has been found to inactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus [1]. A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5-10 minutes after brushing[2].

References

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  1. Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral chemistry and chemotherapy. 16 (2): 129–34. PMID 15889535.  More than one of |number= and |issue= specified (help)
  2. Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.  More than one of |number= and |issue= specified (help)