2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene

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2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
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Systematic (IUPAC) name
2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
Chemical data
Formula C25H40O2
Molar mass 372.582 g/mol[[Script error: No such module "String".]]
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2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene is an analgesic compound which is a cannabinoid agonist. It is a ring-opened cannabinoid derivative, an analogue of cannabidiol. However, unlike cannabidiol, this compound produces potent cannabis-like effects in animals, suggesting it acts as a CB1 agonist.[1]

It can be synthesized by Birch reduction from the nonyl-analog of cannabidiol.[2]

References

  1. ↑ Raj K. Razdan. The Total Synthesis of Cannabinoids. p245. Volume 4 of The Total Synthesis of Natural Products, edited by John Apsimon. Wiley Interscience. May 1981. ISBN 978-0-471-05460-3
  2. ↑ Razdan RK, Pars HG, Thompson WR, Granchelli FE (1974). "Lithium-ammonia reduction of tetrahydrocannabinols". Tetrahedron Letters. 15: 4315. doi:10.1016/S0040-4039(01)92152-5. 
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