3F8
From Self-sufficiency
| Monoclonal antibody | |
|---|---|
| Type | ? |
| Source | Template:Infobox drug/mab source |
| Target | GD2 |
| Clinical data | |
| Routes of administration | intravenous |
| Identifiers | |
| ATC code | none |
3F8 is a murine IgG3[1] monoclonal antibody which binds to GD2.[2]
It has been used in the detection and treatment of neuroblastoma. For imaging neuroblastoma, it is labelled with one of the radioisotopes iodine-124 and iodine-131.[3][4][5]
See also
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
| 40x30px | This monoclonal antibody-related article is a stub. You can help ssf by expanding it. |
- ↑ Kushner BH, Cheung NK (1989). "GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma". Blood. 73 (7): 1936–41. PMID 2653466.
- ↑ "Sloan-Kettering - Neuroblastoma: 3F8 Monoclonal Antibody Therapy Q & A". Retrieved 2008-02-19.
- ↑ "ACS :: New Drug Targets Tough
Childhood Cancer". Retrieved 2008-02-19. - ↑ Yeh SD, Larson SM, Burch L; et al. (1991). "Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities". J. Nucl. Med. 32 (5): 769–76. PMID 1902508.
- ↑ Dauer LT, St Germain J, Williamson MJ; et al. (2007). "Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma". Health Phys. 92 (1): 33–9. doi:10.1097/01.HP.0000231583.32904.6c. PMID 17164597.
Categories:
- Pages with script errors
- Articles which use infobox templates with no data rows
- Drugs that are a monoclonal antibody
- Infobox drug tracked parameters
- Chemical articles without CAS Registry Number
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs not assigned an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- 2Fix
- Pages with broken file links
- Monoclonal antibody stubs
- CS1 maint: Explicit use of et al.
- CS1 maint: Multiple names: authors list
