4-Dimethylaminophenol

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4-Dimethylaminophenol
File:4-Dimethylaminophenol.svg
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 619-60-3
PubChem 22174
ChemSpider 20816
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InChI key JVVRCYWZTJLJSG-UHFFFAOYAU
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C8H11NO
Molar mass 137.179 g/mol
Boiling point

165 °C (0.040 bar)

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.

Uses

4-Dimethylaminophenol has been used as an antidote for cyanide poisoning.[1]

It works by generating methemoglobin. [2]

This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.

In an animal model, it has shown effectiveness when given intramuscularly.[3]

See also

References

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  2. Vick JA, Von Bredow JD (1996). "Effectiveness of intramuscularly administered cyanide antidotes on methemoglobin formation and survival". J Appl Toxicol. 16 (6): 509–16. doi:10.1002/(SICI)1099-1263(199611)16:6<509::AID-JAT382>3.0.CO;2-V. PMID 8956097. 
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