Amidorphin

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Amidorphin
File:Amidorphin.png
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 94885-44-6
PubChem 16132380
ChemSpider 17289039
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style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C131H200N30O43S2
Molar mass 2947.29 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Amidorphin is an endogenous, C-terminally amidated, opioid peptide generated as a cleavage product of proenkephalin A that is widely distributed in the mammalian brain, with particularly high concentrations found in the adrenal medulla, posterior pituitary, and striatum.[1][2] In some brain areas, amidorphin is extensively further reduced into smaller fragments, such as the non-opioid peptide amidorphin-(8-26) which lacks the N-terminal [Met]enkephalin sequence of amidorphin; accordingly, [Met]enkephalin may also be a cleavage product of amidorphin.[3]

See also

References

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Opioids
See also: Opioids template
Opium & alkaloids thereof
Semi-synthetic opium
derivatives
Synthetic opioids
Pyrazolones
Cannabinoids
Anilides
Non-steroidal
anti-inflammatories
See also: NSAIDs template
Propionic acid class
Oxicam class
Acetic acid class
Anthranilic acid
(fenamate) class
Atypical, Adjuvant & Potentiators,
Metabolic agents and miscellaneous
Dynorphin
Endorphin
Enkephalin
Others
Adrenorphin • Amidorphin
  1. ↑ Seizinger BR, Liebisch DC, Gramsch C; et al. (1985). "Isolation and structure of a novel C-terminally amidated opioid peptide, amidorphin, from bovine adrenal medulla". Nature. 313 (5997): 57–9. PMID 3965972. 
  2. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  3. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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