Brodimoprim

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Brodimoprim
File:Brodimoprim.svg
Systematic (IUPAC) name
5-[(4- bromo- 3,5- dimethoxyphenyl) methyl] pyrimidine- 2,4- diamine
Identifiers
CAS Number 56518-41-3
ATC code J01EA02 (WHO)
PubChem CID 68760
ChemSpider 62004
Chemical data
Formula C13H15BrN4O2
Molar mass 339.188 g/mol[[Script error: No such module "String".]]
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Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.

As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase.[1]

References

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  1. Thomson CJ (1993). "Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria". J Chemother. 5 (6): 45864. PMID 8195838.