Ethacridine lactate
From Self-sufficiency
| File:Ethacridinlactat.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
7-ethoxyacridine-3,9-diamine; 2-hydroxypropanoic acid | |
| Identifiers | |
| CAS Number | 442-16-0 |
| PubChem | CID 15789 |
| Chemical data | |
| Formula | C18H21N3O4 |
| Molar mass | 343.37[[Script error: No such module "String".]] |
Ethacridine lactate (ethacridine monolactate monohydrate, acrinol, trade name Rivanol) is an aromatic organic compound based on acridine. Its formal name is 2-ethoxy-6,9-diaminoacridine monolactate monohydrate. It forms orange-yellow crystals with a melting point of 226 °C and it has a stinging smell.
Its primary use is as an antiseptic in solutions of 0.1%.
Ethacridine is also used as an agent for second trimester abortion. Up to 150 ml of a 0.1% solution is instilled extra-amniotically using a foley catheter. After 20 to 40 hours, 'mini labor' ensues. In China, an intra-amniotic method has also been used. Ethacridine as an abortifacient is found to be safer and better tolerated than 20% hypertonic saline.
References
- Obstetrics & Gynecology 1983;61:733-736
- Merck Index, 11th Ed., 3668.
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