Famprofazone

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Famprofazone
File:Famprofazone.png
Systematic (IUPAC) name
1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • ℞ (Prescription only)
Identifiers
CAS Number 22881-35-2
ATC code none
PubChem CID 3326
ChemSpider 3209
Chemical data
Formula C24H31N
Molar mass 377.52 g/mol[[Script error: No such module "String".]]
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Famprofazone (Gewodin, Gewolen) is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan.[1][2][3] It has analgesic, anti-inflammatory, and antipyretic effects.[1][2] Famprofazone has been known to produce methamphetamine as an active metabolite, with 15-20% of an oral dose being converted to it.[4][5] As a result, famprofazone has occasionally been implicated in causing false positives on drug tests for amphetamines.[3]

See also

References

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  1. 1.0 1.1 Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 1932. ISBN 3-88763-075-0. 
  2. 2.0 2.1 Hall, Judith A.; Morton, Ian (1999). Concise dictionary of pharmacological agents: properties and synonyms. Kluwer Academic. p. 342. ISBN 0-7514-0499-3. 
  3. 3.0 3.1 Chan KH, Hsu MC, Tseng CY, Chu WL (2010). "Famprofazone use can be misinterpreted as methamphetamine abuse". Journal of Analytical Toxicology. 34 (6): 347–53. PMID 20663288. 
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  5. Shin HS, Park BB, Choi SN, Oh JJ, Hong CP, Ryu H (1998). "Identification of new urinary metabolites of famprofazone in humans". Journal of Analytical Toxicology. 22 (1): 55–60. PMID 9491970.