MMDA-2

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MMDA-2
File:MMDA-2-structure.png
Systematic (IUPAC) name
1-(6-methoxy-1,3-benzodioxol-5-yl)propan-2-amine
Clinical data
Routes of
administration
Oral, Insufflated, Rectal
Legal status
Legal status
Identifiers
CAS Number 23693-18-7
ATC code none
PubChem CID 90966
ChemSpider 82147
Chemical data
Formula C11H15NO3
Molar mass 209.24 g/mol[[Script error: No such module "String".]]
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2-Methoxy-4,5-methylenedioxyamphetamine (MMDA-2; 6-Methoxy-MDA) is a psychedelic drug of the amphetamine class.[1] It is closely related to MMDA and MDA.[1]

Alexander Shulgin was likely the first to synthesize MMDA-2.[1] In his book PiHKAL, the dose is listed as 25-50 mg, and the duration is listed as 8-12 hours.[1] Shulgin reports that MMDA-2 produces effects such as enhanced awareness, empathy, and visual facilitation and distortion, as well as some side effects like gastrointestinal upset and appetite loss.[1] He states that 30 mg is very similar to 80 mg of MDA, and also remarks that it would be impossible for anyone to have a bad experience on the drug at that dose.[1]

Scientific research has shown that MMDA-2, unlike MMDA, but similarly to 6-methyl-MDA, is only very weak at inducing the release of serotonin or dopamine,[2] and accordingly, does not produce amphetamine-appropriate responding in animals in drug discrimination studies.[3] Instead, MMDA-2 is likely to act as a pure 5-HT2 receptor agonist similarly to the DOx series of compounds, with activation of the 5-HT2A receptor conferring its psychedelic effects.[4]

MMDA-2 has been sold as a designer drug in Japan.[5]

See also

References

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External links

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Ann Shulgin; Alexander Shulgin (1991). Pihkal: A Chemical Love Story. Transform Press. ISBN 0-9630096-0-5. 
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  4. Clare BW (2002). "QSAR of benzene derivatives: comparison of classical descriptors, quantum theoretic parameters and flip regression, exemplified by phenylalkylamine hallucinogens" (PDF). Journal of Computer-aided Molecular Design. 16 (8-9): 611–33. PMID 12602954. 
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