Naphazoline

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Naphazoline
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Systematic (IUPAC) name
2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
Clinical data
Routes of
administration
Topical
Identifiers
CAS Number 835-31-4
ATC code R01AA08 (WHO)
PubChem CID 4436
Chemical data
Formula C14H14N2
Molar mass 210.274[[Script error: No such module "String".]]
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Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.[1]

It has the molecular formula C14H14N2.HCl and a molecular weight of 246.73 g/mol.

Warnings and contraindications

A few warnings and contraindications that apply to all naphazoline-containing substances intended for medicinal use are:

A possible association with stroke has been suggested.[2]

References

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fa:نفازولین

it:Nafazolina hu:Nafazolin ja:ナファゾリン pl:Nafazolina pt:Nafazolina

ru:Нафазолин
  1. "Ophthalmology: naphazoline". Tarascon Pocket Pharmacopoeia 2009. Jones and Bartlett Publishers. 2008. ISBN 0763765724. 
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