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...an activate and influence biochemical behaviour of most cells. The steroid/receptor complexes dimerise and interact with cellular DNA in the nucleus, binding t

...INR should be monitored closely. They may also interact with the [[GABA A receptor]] and cause neurological symptoms; this effect is augmented by certain [[no

...the experiments in rats, via the action on [[arachidonic acid]] and [[NMDA receptor]]s cascade.<ref name="Gutton">{{Cite journal|author=Guitton MJ, Caston J, R

...enolol''' ('''Tenormin''') is a selective [[beta-1 receptor|β₁ receptor]] [[receptor_antagonist|antagonist]], a [[drug]] belonging to the group of ...lpha-agonists (e.g. [[clonidine]]), [[ACE Inhibitor]]s or [[Angiotensin II receptor antagonist]]s such as losartan can also be given additionally. Exert cautio

...development, the &alpha;₆&beta;₂&gamma;₂ receptor increases in expression in cerebellar granule neurons, corresponding to inc

...D₃]], [[Dopamine D4 receptor|D₄]], and [[Dopamine D5 receptor|D₅]]—and their variants. Dopamine is produced in several areas Via the [[dopamine receptor]]s, D_1-5, dopamine reduces the influence of the indirect pathway

'''Timolol maleate''' is a non-selective [[beta blocker|beta-adrenergic receptor blocker]]. In its oral form ('''Blocadren'''), it is used to treat [[hypert

...short-acting [[beta2-adrenergic receptor agonist|β₂-adrenergic receptor agonist]] used for the relief of [[bronchospasm]] in conditions such as [[a Salbutamol was the first selective Β2-receptor agonist to be marketed — in 1968. It was first sold by Allen & Hanburys u

...s Type I and Type II receptor agonist), or [[RU28362]] (a specific Type II receptor agonist), to adrenalectomized animals induced changes in [[leukocyte distri .... Aldosterone and cortisol have similar affinity for the mineralocorticoid receptor however, glucocorticoids circulate at roughly 100 times the level of minera

{{See also|Adrenergic receptor}} ...ues. Its actions vary by tissue type and tissue expression of [[adrenergic receptor]]s. For example, epinephrine causes [[smooth muscle]] relaxation in the air

...and slightly potentiates [[GABAA receptor|GABA_A]] and [[glycine receptor]]s.<ref name="pmid11020766">{{cite journal|author = Yamakura T, Harris RA|t ...7862891}}</ref> Indeed, in humans given 30% N₂O, benzodiazepine receptor antagonists reduced the subjective reports of feeling "high", but did not a

...that apparently only reacted to morphine: the mu3 [[Opioid receptor|opiate receptor]] in human tissue.<ref>{{cite journal |author=Zhu W, Cadet P, Baggerman G, ...de release in the mammalian gastrointestinal tract via the micro(3) opiate receptor subtype: a hormonal role for endogenous morphine|journal=Journal of Physiol

...inding to the benzodiazepine site on the [[GABAA receptor|GABA_A receptor]] leading to [[central nervous system]] depression.<ref name="Riss-2008"/> ...irst2 = R. | last3 = Hösl | first3 = K. | title = Subtype-selective GABAA receptor mimetics--novel antihyperalgesic agents? | url = http://www.springerlink.co

...nn M"/> 3) Surface enterocytes also express high levels of [[Interleukin-1 receptor]] (IL-1R) -containing inhibitory molecule. IL-1R are also referred to as si ...mponent that monitors and responds to changes in the environment. When the receptor senses a stimulus, it sends information to a '''control center''', the comp

...url=}}</ref> There is some evidence that it may act at [[Beta-3 adrenergic receptor|β₃ adrenergic receptors]].<ref name="pmid10344530">{{cite journ

...ction there. The cytokine factors then bind with [[endothelium|endothelial receptor]]s on vessel walls, or interact with local [[microglial cell]]s. When these ...ein]] (LBP) binds to LPS. The LBP–LPS complex then binds to the [[CD14]] receptor of a nearby [[macrophage]]. This binding results in the synthesis and relea

...[[Complement Receptor 3|Macrophage-1 antigen]] ([[CD18]]) [[cell receptor|receptor]] on immune cells.<ref name=pmid15084502>{{cite pmid|15084502}} (review)</r ...recent{{When|date=May 2010}} study reported that the [[selective estrogen receptor modulator]] [[raloxifene]] has similar benefits to [[tamoxifen]] in prevent

...i, C; Cacciarini, M; Pergoli, R; Roelens, S|date=2004|title=A New Tripodal Receptor for Molecular Recognition of Monosaccharides. A Paradigm for Assessing Glyc

...biochemistry]] host-guest complexes are known as [[receptor (biochemistry)|receptor]]-ligand complexes; they are formed primarily by [[non-covalent bond]]ing. ...ther blocks a receptor, an [[antagonist]] which forms a strong complex the receptor, or activate it, an [[agonist]], is an important pathway to [[drug discover

...eriodic syndrome]] (Familial Hibernian fever, TRAPS, Tumor necrosis factor receptor associated periodic syndrome) *[[Leukotriene receptor antagonist-associated Churg–Strauss syndrome]]

* [[Hypercholesterolemia due to LDL receptor deficiency]] * [[Hyperthyroidism due to mutations in TSH receptor]]

* [[Mutations in estradiol receptor]]

* [[Complement component receptor 1]]

| Dihydrotestosterone receptor deficiency <br><small>''see'' [[androgen insensitivity syndrome]] </small>

...a gravis]]* results from the presence of antibodies to the [[acetylcholine receptor]]. Signs include [[megaesophagus]] and muscle weakness.<ref>{{cite web | ti

...calcium channel blockers (i.e. verapamil, deltiazem, nifedipine) and Beta-receptor antagonists (i.e. propranolol). Beta-receptor antagonists do not cause vasodilation but they do decrease the heart's dema

!Receptor <br/> (↑ = opens. ↓ = closes) <ref name=boron/> <br> <font size=1> On [ |rowspan=2| [[nitric oxide]] || ↑[[NO receptor]] on smooth muscle || ↑[[cyclic GMP|cGMP]] --> ↑[[protein kinase g|PKG]

..., into the [[sarcoplasm]] of muscle cell. Calcium ions bind to [[ryanodine receptor]]s on the [[sarcoplasmic reticulum]] causing a flux of calcium ions to the

...tp://www.nature.com/bjp/journal/v143/n4/full/0705974a.html "Selective GABA-receptor actions of amobarbital on thalamic neurons."] ''British Journal of Pharmaco ...hader RI | title=Acute barbiturate administration increases benzodiazepine receptor binding in vivo | journal=Psychopharmacology (Berl) | volume=96 | issue=3 |

...the [[Alpha-4 beta-2 nicotinic receptor|α4β2]] [[nicotinic acetylcholine receptor#Subunits|subtypes]]. It was developed as a less toxic [[analog (chemistry)|

...nic acetylcholine receptor]]s selective for the [[Alpha-4 beta-2 nicotinic receptor|α4β2]] subtype, and has been researched for use as an [[analgesic]], alth

...brain: isolation, structure elucidation, and interactions with the opiate receptor |journal=Proc Natl Acad Sci USA |volume=73 |issue=7 |pages=2515–9 |year=1 ...for the κ₁ opioid receptors. μ opioid receptors are the main receptor through which [[morphine]] acts. Classically, μ opioid receptors are presy

...nti-inflammatory action is induced through the activation of [[cannabinoid receptor]]s which prevents [[microglia]]l activation that elicits the inflammation.

...Tomasini MC, Gessa GL, Bebe BW, Tanganelli S, Antonelli T. The Cannabinoid Receptor Agonist WIN 55,212-2 Regulates Glutamate Transmission in Rat Cerebral Corte ...t.'' 1997 '''221''' 157</ref>. It activates p42 and p44 [[MAP kinase]] via receptor-mediated signaling.<ref>M. Bouaboula ''et al. Biochem. J.'' 1995 '''312'''

...3.4nM and selectivity of around 200x for CB₂ over [[Cannabinoid receptor type 1|CB₁]] receptors. It was discovered by, and named after, [ ...antiinflamatory action is induced through agonist action at [[cannabinoid receptor]]s, which prevents [[microglia]]l activation that elicits the inflammation.

...bind to the centrally expressed cannabinoid receptor type-1 ([[Cannabinoid receptor 1|CB₁]]) and therefore does not exert psychomimetic effects.

...cannabinoid receptors]], acting as an [[inverse agonist]] at [[Cannabinoid receptor 1|CB₁]] receptors.<ref name="pmid18077343">{{cite journal |autho

...nabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function|journal = [[Pharmacology]]|volume = 83|issue = 4|pages = 217–222 ...acting on a [[cannabinoid receptor]] on the [[ciliary body]] called the CB receptor.<ref>{{cite journal|author = Goldberg J, Flowerdew G, Smith E, Brody JA, Ts

...ub>]], [[GABAA-rho receptor|GABA_A-ρ]], [[glycine]] and [[5-HT3 receptor|5-HT₃ receptors]] that are composed of five [[protein subunit]]s ...e journal | author = Sine S, Engel A | title = Recent advances in Cys-loop receptor structure and function. | journal = Nature | volume = 440 | issue = 7083 |

:{{Main|Nerve growth factor receptor}} There are two classes of [[receptor (biochemistry)|receptor]]s for neurotrophins: p75 and the "Trk" family of [[Tyrosine kinase]]s rece

...comparisons to the signaling role of the surface [[transmembrane receptor|receptor]] protein [[Notch signaling|Notch]].<ref name="Selkoe">{{cite journal | aut *{{cite journal | author=Coulson EJ |title=Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease? |journal=J. Neuroche

...hormone]] on its target. The hormone activates or deactivates [[ionotropic receptor]]s (ligand-gated ion channels). The effect can be either positive or negati ...ionotropic effect on [[heart muscle]], when binding to [[beta-1 adrenergic receptor]]s on this tissue<ref name=purves> Neuroscience (Purves), Third Edition, ta

...=|accessdate=}}</ref>&nbsp; Signal transduction starts with a signal to a receptor, and ends with a change in cell function. ...de the cell.&nbsp; The chemical signal binds to the outer portion of the receptor, changing its shape and conveying another signal inside the cell.&nbsp; So

*Some [[transient receptor potential channel]]s: This group of channels, normally referred to simply a ...nion-permeable γ-aminobutyric acid-gated [[GABA receptor|GABA_A receptor]].

...els''' ('''LGICs''') are one type of ionotropic receptor or channel-linked receptor. They are a group of [[transmembrane]] [[ion channel]]s that are opened or ...tle = The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function | journal = Biochem. Soc. Trans. | volume = 32 | issu

...hydromorphone, related to the morphine molecule, is a primary [[mu opioid receptor|μ]] agonist]. Although this can lead to addiction and reward-seeking behav Hydromorphone, a semi-synthetic [[Opioid receptor#The μ-opioid receptor|μ-opioid]] [[agonist]], is a [[hydrogenation|hydrogenated]] [[ketone]] of

...8}}</ref> In addition, it is a synthetic strong agonist at the [[mu opioid receptor|μ-opioid]] receptors. Historically it has been used to treat [[breakthroug

...lly unlike [[morphine]] or [[heroin]], methadone also acts on the [[opioid receptor]]s and thus produces many of the same effects. Methadone is also used in ma ...receptor, but also has some affinity for the [[NMDA]] ionotropic glutamate receptor. It is metabolized by the enzymes [[CYP3A4]], [[CYP2B6]] and [[CYP2D6]], wi

...Receptor antagonist|antagonist]] of N-methyl-d-aspartate receptors ([[NMDA receptor]]s). These receptors exacerbate the damage from [[oxygen deprivation]] and [[Category:NMDA receptor antagonists]]

...0s by Dr. [[Henri Laborit]] to use in studying the neurotransmitter [[GABA receptor|GABA]].<ref>{{cite journal | author = H. Laborit, J.M. Jouany, J. Gerald, F ...}</ref> and it is a weak agonist at the [[GABA receptor|GABA_B]] receptor, which is [[inhibitory]].<ref name="mechanism" /> GHB is a naturally-occurr