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...last5=Pussard | first5=E | pmc=1458599 }}</ref> The main problem with the rectal route is that the dose can be expelled before it is completely absorbed; th ==Regulation by the United States Food and Drug Administration==

| routes_of_administration = Oral, rectal, parenteral ([[intramuscular injection|intramuscular]] and [[intravenous th ...dreds of patients died or were injured as a result. A U.S. [[Food and Drug Administration]] investigation was highly critical of Winthrop and the scandal led to the

| bioavailability = 70-100% oral, 24.4% for rectal and intravenous administration It was approved by the [[USA]] [[Food and Drug Administration]] in 1953 for use in [[seizure]]s.

| bioavailability = 100% (oral)<br />59–94% (rectal) | routes_of_administration = oral, [[topical]], [[suppository|rectal]], [[intravenous|IV]], [[vaginal]]

| routes_of_administration = oral, rectal<ref name="parrott1976">{{Cite doi|10.1002/jps.2600660713}}</ref> ...mits can be fixed) of the Council Regulation 2377/90. The [[Food and Drug Administration]] (FDA) of the United States has prohibited [[furaltadone]] since February

| routes_of_administration = Oral, [[suppository|rectal]], [[intravenous therapy|IV]], [[intramuscular injection|IM]], [[topical]] ...n]]s ([[Intramuscular injection|IM]]/[[Intravenous therapy|IV]] [[Route of administration|route]] preferred).<ref name=rxlisttabind />

| routes_of_administration = Most commonly oral, also rectal. [[Lysine acetylsalicylate]] may be given [[intravenous therapy|IV]] or [[i ...al infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study| journal = The New England journal of medicine| date = 19

| routes_of_administration = Oral, rectal, topical, and [[intravenous therapy|intravenous]] ==Typical administration==

...g]]), [[Insufflation (medicine)|insufflation]] ([[snorting]]), [[oral]], [[rectal]], [[subcutaneous]] (S.C), [[intramuscular]] (I.M), [[intravenous]] (I.V), ...ractise via unsupervised injection but one used medically with oral opioid administration and under direct supervision of a doctor and nurse via the IV and SC routes

| routes_of_administration = [[Mouth|Oral]], [[rectal]], [[Intravenous therapy|intravenous]] ....1].</ref> The onset of analgesia is approximately 11 minutes after [[oral administration]] of paracetamol,<ref>{{cite doi|10.1093/bja/aei109}}</ref> and its [[half

* For oral administration: * For parenteral administration:

...rface of the [[human skin|skin]], [[transdermal]]ly, [[ophthalmic]]ally, [[rectal]]ly or [[vagina]]lly. A very liquidy emulsion may also be used [[oral]]ly, {{Routes of administration}}

| routes_of_administration = oral, [[rectal]] ...oral ingestion as tablets or granules, and for rectal administration as a rectal [[suppository]], suspension or [[enema]]s. It is marketed under a variety o

...ne sufferers. Br J Clin Pharmacol 1983; 16: 695–9.</ref> (Enhanced by co-administration of caffeine <ref name="kinetics1" />)

...ne designed to prevent cancer available. In 2006, the [[U.S. Food and Drug Administration]] approved a [[human papilloma virus]] vaccine, called [[Gardasil]]. The va ...t [[testicular cancer]]. Prostate cancer can be screened using a [[digital rectal exam]] along with [[prostate specific antigen]] (PSA) blood testing, though

| routes_of_administration = Oral, [[IM]], [[IV]], Rectal ...G, Deutsch SI, Greenblatt DJ, Paul SM, Shader RI | title=Acute barbiturate administration increases benzodiazepine receptor binding in vivo | journal=Psychopharmacol

...stion, transdermal patch, intravenous injection, sublingual absorption, or rectal suppository. Once in the body, most cannabinoids are metabolized in the [[l ...e cannabis [[metabolite]]s can be detected in the body several weeks after administration.

...netics and bioavailability of hydromorphone following intravenous and oral administration to human subjects | journal = J Clin Pharmacol | volume = 21 | issue = 4 | ...ministration = oral, intramuscular, intravenous, subcutaneous, intranasal, rectal, sublingual, transmucosal, buccal, transdermal (experimental)

| routes_of_administration = oral, intravenous, insufflation, sublingual, rectal ...[CYP2D6]], with great variability between individuals. Its main [[route of administration]] is oral. Adverse effects include [[hypoventilation]], [[constipation]] an

| routes_of_administration = oral, intranasal, rectal ...proved by the [[Food and Drug Administration (United States)|Food and Drug Administration]] on 23 March 1943 for sale in the United States and approved by Health Can

...estinal [[hemorrhage]], gastrointestinal perforation, [[melena]], [[rectum|rectal]] bleeding, [[gastritis]], [[eructation]], [[anorexia (symptom)|anorexia]], Ketorolac is not recommended for pre-[[Surgery|operative]] analgesia or co-administration with [[anesthesia]] because it inhibits [[platelet]] aggregation and thus m

...g regimens (related to the compound's [[elimination half-life]]), route of administration, and tolerability profile. Some more common examples are given below. ...the incidence of gastrointestinal ADRs. Similarly, there is a belief that rectal formulations may reduce gastrointestinal ADRs. However, in consideration of

...Choice|elective]] human [[tracheotomy]] to be performed for the purpose of administration of general anesthesia.<ref name=Trendelenburg1871/><ref name=Hargrave1934/> ...al application of [[local anesthetic]]s to the [[Mucous membrane|mucosa]], rectal anesthesia, or [[Intravenous therapy|intravenous]] anesthesia. While otherw

...[[plant]] or [[food]] of sorts, among many others. Notably, the [[route of administration]] (ROA) for [[drug delivery]] is dependent on the dosage form of the [[chem ...ug, since different [[medical condition]]s can warrant different routes of administration. For example, persistent [[nausea]] and [[emesis]] or [[vomiting]] may make